The intricate mechanisms of the kidney are a constant focus for medical and pharmaceutical research. Understanding how specific compounds influence renal function is critical for developing new treatments for kidney-related diseases. In this context, 2,4,6-Triaminopyrimidine (CAS 1004-38-2) emerges as a significant research chemical, particularly for its role in modulating paracellular pathways.

What is 2,4,6-Triaminopyrimidine?

2,4,6-Triaminopyrimidine, identified by its CAS number 1004-38-2, is an organic cation with the molecular formula C4H7N5. It is known for its specific chemical structure that allows it to interact with cellular transport mechanisms. Its physical properties, such as appearance as a white powder and a melting point between 249-251°C, are important for handling and formulation.

Mechanism in Kidney Research

The primary scientific interest in 2,4,6-Triaminopyrimidine lies in its ability to block paracellular conductance pathways in various epithelia, including those found in the rat kidney. These pathways are crucial for the selective movement of ions and molecules between cells. By blocking these channels, 2,4,6-Triaminopyrimidine influences the excretion of essential electrolytes like sodium and potassium. This makes it an invaluable compound for researchers investigating:

  • Renal ion transport mechanisms
  • The regulation of sodium and potassium balance
  • The development of therapeutic agents targeting kidney function

Researchers seeking to buy this compound for such studies will look for guaranteed high purity to ensure accurate and reproducible results. The availability of reliable data, including Certificates of Analysis (CoA), is also essential for scientific validation.

Sourcing High-Purity 2,4,6-Triaminopyrimidine

For those involved in pharmaceutical research and development, securing a dependable source of 2,4,6-Triaminopyrimidine is key. As a reputable chemical supplier and manufacturer in China, we specialize in providing high-quality intermediates like 2,4,6-Triaminopyrimidine (CAS 1004-38-2). We understand the stringent requirements of scientific research and are committed to delivering products with guaranteed purity (e.g., 97%) and comprehensive documentation. Our goal is to support innovation by providing researchers with the essential building blocks they need. We encourage inquiries for bulk purchases and free samples to facilitate your research endeavors.

By understanding the specific applications and sourcing reliable materials, researchers can effectively leverage compounds like 2,4,6-Triaminopyrimidine to advance their understanding of kidney physiology and develop novel therapeutic solutions.