Organic synthesis is the backbone of innovation in sectors like pharmaceuticals and agrochemicals. At the heart of many synthetic routes lie versatile intermediates, and 3,5-Dibromoacetophenone (CAS 14401-73-1) stands out as a prime example. Its unique chemical structure and reactivity make it an indispensable tool for scientists seeking to construct complex molecules. Understanding its properties and applications is crucial for researchers aiming to optimize their synthetic strategies and for procurement managers needing to source this vital compound reliably.

Chemical Profile and Reactivity of 3,5-Dibromoacetophenone

3,5-Dibromoacetophenone, also known by its IUPAC name 1-(3,5-dibromophenyl)ethanone, is an aromatic ketone characterized by two bromine substituents at the meta positions of the phenyl ring. This dibrominated structure imparts specific electronic properties and reactivity. The presence of the carbonyl group allows for nucleophilic addition reactions, while the bromine atoms are excellent leaving groups, making the molecule amenable to various palladium-catalyzed cross-coupling reactions, such as Suzuki, Heck, and Sonogashira couplings. These reactions are fundamental in building larger, more complex organic frameworks. Researchers often search for this compound with high purity, typically 98% or more, to ensure predictable reaction outcomes.

Applications in Pharmaceutical Research and Development

In the pharmaceutical industry, 3,5-Dibromoacetophenone serves as a critical intermediate for synthesizing Active Pharmaceutical Ingredients (APIs). Its structure can be modified through various reactions to create novel drug candidates with potential therapeutic benefits. For example, it can be a starting point for compounds targeting specific biological pathways. Scientists in medicinal chemistry value this intermediate for its ability to introduce halogen atoms and a functionalized carbonyl group, which are common features in many biologically active molecules. When looking to buy this compound for pharmaceutical R&D, it is imperative to source it from a reputable manufacturer that guarantees high purity and provides thorough documentation.

Role in Agrochemical Synthesis

The agrochemical sector also heavily relies on intermediates like 3,5-Dibromoacetophenone. It plays a role in the synthesis of pesticides, herbicides, and fungicides. The bromine atoms can be retained or further functionalized to create molecules with specific biological activities that protect crops from pests and diseases. The demand for such intermediates is driven by the need for more effective and environmentally friendly crop protection solutions. Sourcing this chemical from a reliable supplier in China ensures access to high-quality material at competitive prices, supporting the development and large-scale production of these essential agricultural products.

Sourcing Strategies for Researchers and Buyers

For researchers and procurement specialists, identifying a trustworthy manufacturer of 3,5-Dibromoacetophenone is key. Companies specializing in fine chemical synthesis, particularly those in China, often provide excellent value. When you need to purchase this compound, look for suppliers who clearly state purity levels, offer detailed technical data (like SDS and COA), and have a responsive customer service team. Obtaining a timely quote and ensuring a stable supply are vital for project continuity. By understanding the chemical's significance and partnering with reliable sources, you can effectively leverage 3,5-Dibromoacetophenone in your advanced organic synthesis endeavors.