The field of biochemistry is continuously seeking novel tools and reagents to unravel complex biological mechanisms. Among the array of specialized compounds, modified amino acids like 3,5-Diiodo-L-tyrosine dihydrate (CAS 18835-59-1) offer unique advantages for research. This article highlights the critical applications of this compound in biochemical studies and provides guidance for researchers on where to buy it from dependable sources.

3,5-Diiodo-L-tyrosine dihydrate is fundamentally an iodinated derivative of the essential amino acid tyrosine. The introduction of iodine atoms at the 3 and 5 positions of the phenyl ring significantly alters its chemical properties, making it a valuable reagent for specific biochemical investigations. Its structural similarity to tyrosine allows it to be incorporated into peptide chains or mimic the behavior of tyrosine in protein interactions, enabling researchers to study these processes in detail.

One of the primary areas where 3,5-Diiodo-L-tyrosine dihydrate finds application is in the study of thyroid hormone synthesis and metabolism. Thyroid hormones, such as thyroxine (T4) and triiodothyronine (T3), are derived from tyrosine and incorporate iodine. Researchers utilize iodinated tyrosine derivatives like 3,5-Diiodo-L-tyrosine dihydrate to better understand the pathways of iodination, hormone formation, and the mechanisms by which these hormones regulate bodily functions. This makes it an indispensable tool for endocrinologists and biochemists focused on thyroid-related research.

Furthermore, this compound is employed in molecular biology and proteomics to investigate protein structure and function. By substituting natural tyrosine residues with their iodinated counterparts, scientists can probe protein folding, enzyme activity, and ligand binding. This substitution can introduce spectroscopic handles or alter the electronic environment of the protein, providing insights that might not be obtainable with the unmodified amino acid. When seeking to buy this for such applications, ensuring a minimum purity of 99% is standard practice.

For academic institutions and research laboratories, sourcing high-quality 3,5-Diiodo-L-tyrosine dihydrate is crucial for experimental accuracy. Reputable suppliers and manufacturers, particularly those located in regions with strong chemical production capabilities like China, offer this compound. It is advisable for researchers to obtain quotes and check the specifications, including purity levels and the availability of Certificates of Analysis, before making a purchase. Exploring the product catalogs of established fine chemical suppliers is often the most efficient way to locate suitable sources.

In essence, 3,5-Diiodo-L-tyrosine dihydrate is more than just a chemical reagent; it is a gateway to deeper understanding in biochemistry. Its applications in thyroid hormone research, protein structure analysis, and other biochemical investigations underscore its importance. By partnering with reliable manufacturers and suppliers, researchers can access the high-purity compounds necessary to push the boundaries of scientific discovery.