The backbone of many advanced chemical processes lies in the availability of versatile and reliable intermediates. 3-Chloro-2-iodopyridine (CAS: 77332-89-9) stands out as a prime example, serving as a critical component in sophisticated organic synthesis. Its unique structure, featuring both chlorine and iodine atoms on a pyridine ring, endows it with distinct reactivity that chemists leverage for creating complex molecules. For R&D scientists and procurement specialists looking to buy this compound, understanding its chemical nuances and sourcing from reputable suppliers is essential.

Chemical Profile and Reactivity

3-Chloro-2-iodopyridine typically presents as a gray-white crystalline solid with a guaranteed assay of $\ge 98.0\%$. This high purity is vital for predictable and efficient reaction outcomes, especially in sensitive applications like pharmaceutical synthesis. The pyridine ring itself is a foundational heterocyclic aromatic system. The presence of two different halogen atoms—chlorine and iodine—at adjacent positions (2 and 3 respectively) on this ring significantly influences its reactivity. The iodine atom, being a good leaving group, makes the compound particularly amenable to metal-catalyzed cross-coupling reactions, such as Suzuki, Heck, or Sonogashira couplings. These reactions are cornerstones of modern organic synthesis for carbon-carbon bond formation. The chlorine atom can also participate in various substitution or coupling reactions, albeit often requiring different conditions than iodine, offering a pathway for selective functionalization. This dual reactivity makes it an exceptionally versatile building block.

Synthetic Utility and Applications

The primary value of 3-Chloro-2-iodopyridine lies in its role as an intermediate. It's extensively used in:

  • Drug Discovery: Its structure is frequently incorporated into the synthesis of novel drug candidates, including those with potential anticancer, antiviral, and anti-inflammatory properties. Researchers frequently search for '3-chloro-2-iodopyridine for sale' to obtain this vital precursor for their medicinal chemistry programs.
  • Agrochemical Innovation: It serves as a key component in the creation of advanced pesticides and herbicides, contributing to more effective and targeted crop protection solutions.
  • Materials Science: The compound can be utilized in the synthesis of specialized polymers and electronic materials where precise molecular architecture is required.

Sourcing from a Trusted Manufacturer in China

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of high-quality 3-Chloro-2-iodopyridine. We understand the critical importance of purity and consistency for organic synthesis intermediates. By partnering with reliable manufacturers in China, we ensure that our clients receive products that meet stringent specifications, offering competitive prices for bulk requirements. Whether you are initiating a new research project or scaling up production, our commitment is to provide you with a dependable supply of this essential intermediate. Contact us to learn more about our product offerings and to request a quotation.