In the intricate world of pharmaceutical manufacturing, the selection and sourcing of raw materials and intermediates are foundational to the entire process. 3-Nitropropiophenone, identified by its CAS number 17408-16-1, stands out as a particularly important compound within this landscape. This article delves into the significance of 3-Nitropropiophenone as a pharmaceutical intermediate, detailing its chemical characteristics and its crucial role in the synthesis of Active Pharmaceutical Ingredients (APIs).

Understanding 3-Nitropropiophenone: A Chemist's Perspective

3-Nitropropiophenone, with the chemical formula C9H9NO3 and a molecular weight of 179.17 g/mol, is a nitro-substituted ketone. The presence of the nitro group (-NO2) and the ketone carbonyl group (C=O) provides reactive sites that chemists can exploit for a wide range of synthetic transformations. Its physical form is typically a white powder, and it possesses a boiling point of 254.5 °C at atmospheric pressure. These attributes make it a stable and manageable compound for laboratory and industrial-scale synthesis.

Applications in API Synthesis

The primary utility of 3-Nitropropiophenone lies in its function as an intermediate for APIs. In this capacity, it is not the final drug product but rather a key building block that undergoes further chemical reactions to form the active molecule. The nitro group can be reduced to an amine, a common step in creating nitrogen-containing heterocycles or amine derivatives found in many drug molecules. The ketone functionality can also be modified through various reactions like Grignard additions, reductions, or Wittig reactions, allowing for the introduction of diverse side chains and structural complexity.

For pharmaceutical companies and R&D departments, having a reliable supplier for intermediates like 3-Nitropropiophenone is essential. The ability to purchase this compound with a guaranteed purity of ≥99% ensures that subsequent reactions proceed efficiently and yield the desired API with minimal byproducts. Manufacturers who can consistently deliver this quality, coupled with competitive pricing and stable supply, become invaluable partners in the drug development pipeline.

The Importance of Sourcing from Trusted Manufacturers

When sourcing 3-Nitropropiophenone, it is vital to engage with experienced manufacturers and suppliers. A reputable supplier will not only guarantee the purity and specifications but also provide necessary documentation and support. For instance, understanding the safety data and handling procedures for this chemical is crucial for laboratory and plant personnel. As a manufacturer in China, we focus on delivering high-quality intermediates, including 3-Nitropropiophenone, to meet the global demand from the pharmaceutical sector. Our commitment is to be a reliable partner, ensuring that researchers and production teams have access to the essential materials they need.

How to Purchase 3-Nitropropiophenone

If your research or manufacturing processes require 3-Nitropropiophenone, we invite you to connect with us. We are a dedicated manufacturer and supplier committed to excellence in chemical synthesis. By providing high-purity intermediates, we aim to support the advancement of pharmaceutical science and the production of life-saving medicines. Contact us today to inquire about pricing, availability, and to place an order for 3-Nitropropiophenone (CAS 17408-16-1).