In the realm of advanced chemical synthesis, the incorporation of fluorine atoms into organic molecules can dramatically alter their properties, leading to enhanced efficacy, metabolic stability, and bioavailability. Among the valuable fluorinated building blocks available to chemists, 3,3,3-Trifluoro-DL-Alanine (CAS 17463-43-3) stands out as a particularly versatile intermediate. Its unique structure makes it an indispensable tool for researchers and manufacturers in the pharmaceutical and fine chemical industries. As a leading supplier of such critical compounds, NINGBO INNO PHARMCHEM CO.,LTD. understands the importance of providing high-quality materials for groundbreaking research and development.

Understanding the Chemistry: What Makes 3,3,3-Trifluoro-DL-Alanine Unique?

3,3,3-Trifluoro-DL-Alanine is a modified amino acid where the three hydrogen atoms on the beta-carbon of alanine are replaced by fluorine atoms. This trifluoromethyl group (–CF3) is highly electronegative and lipophilic, imparting distinct chemical and physical characteristics to the molecule. Its molecular formula, C3H4F3NO2, and molecular weight of 143.06 hint at its role as a precise building block. Its utility lies in its ability to introduce the trifluoromethyl moiety into target molecules, a modification often sought after in drug design to improve pharmacokinetic properties.

Applications in Pharmaceutical Development

The primary application for 3,3,3-Trifluoro-DL-Alanine lies in its role as a pharmaceutical intermediate. It serves as a key starting material or synthon in the multi-step synthesis of various active pharmaceutical ingredients (APIs). The incorporation of the –CF3 group can influence a drug candidate's:

  • Metabolic Stability: The strong carbon-fluorine bond is resistant to enzymatic cleavage, prolonging the drug's half-life in the body.
  • Lipophilicity: The trifluoromethyl group can increase a molecule's lipid solubility, aiding in its absorption and distribution across biological membranes.
  • Binding Affinity: The electronic effects of fluorine can alter molecular interactions with biological targets, potentially enhancing drug potency.

Researchers and manufacturers looking to buy this compound for these advanced applications can rely on reputable suppliers for the necessary purity and consistency.

Role in Organic Synthesis and Beyond

Beyond pharmaceuticals, 3,3,3-Trifluoro-DL-Alanine is a valuable reagent in broader organic synthesis. It can be used to create novel fluorinated peptides, agrochemicals, and specialty materials. Its presence in chemical catalogues signifies its growing importance as a foundational component for innovative chemical research. When seeking to purchase this chemical, verifying the supplier's adherence to quality standards, such as the 98% purity often specified, is paramount.

Sourcing from a Trusted Manufacturer

For businesses requiring a consistent and high-quality supply of 3,3,3-Trifluoro-DL-Alanine (CAS 17463-43-3), partnering with a reliable Chinese manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. is a strategic advantage. We provide essential intermediates that drive innovation in chemical and pharmaceutical industries, ensuring that your synthesis projects benefit from the highest standards of purity and production. If you need to buy this compound, contact us for a quote and discuss your specific requirements.