The pharmaceutical landscape is constantly evolving, with advanced therapeutic agents addressing complex diseases. Obeticholic acid, a potent drug for treating conditions like primary biliary cirrhosis and nonalcoholic fatty liver disease, relies on specific precursor molecules for its synthesis. One such critical component is 3α-Hydroxy-7-oxo-5β-cholanic acid (CAS 4651-67-6).

Understanding Obeticholic Acid and its Synthesis

Obeticholic acid is a farnesoid X receptor (FXR) agonist, playing a vital role in regulating bile acid and lipid metabolism. Its therapeutic efficacy stems from its ability to modulate these pathways. The synthesis of Obeticholic acid involves several chemical steps, and the quality of the starting materials directly impacts the yield and purity of the final active pharmaceutical ingredient (API). 3α-Hydroxy-7-oxo-5β-cholanic acid is a crucial chiral intermediate in this synthetic route.

3α-Hydroxy-7-oxo-5β-cholanic Acid: Properties and Applications

This bile acid derivative, identified by CAS 4651-67-6, typically appears as a white powder. Its molecular structure, featuring specific hydroxyl and oxo groups on a cholanic acid backbone, makes it an ideal precursor for further chemical modifications required to produce Obeticholic acid. As an intermediate in organic synthesis and pharmaceutical research and development, its availability and consistent quality are paramount for researchers and manufacturers aiming to buy this compound.

Sourcing Strategy: Finding a Reliable Manufacturer

For companies looking to procure this essential intermediate, identifying a trustworthy supplier is key. We are a prominent manufacturer based in China, specializing in high-purity fine chemicals and pharmaceutical intermediates. Our expertise ensures that the 3α-Hydroxy-7-oxo-5β-cholanic acid we supply meets the rigorous demands of pharmaceutical synthesis. We understand the importance of securing a stable supply chain and offer competitive prices for bulk quantities, making us an ideal partner for your Obeticholic acid production needs.

Conclusion

The role of 3α-Hydroxy-7-oxo-5β-cholanic acid in the synthesis of Obeticholic acid cannot be overstated. By partnering with a reliable manufacturer like ourselves, pharmaceutical companies can ensure access to a high-quality, cost-effective intermediate, facilitating the efficient production of this important therapeutic agent. We encourage you to contact us to discuss your specific requirements and how we can support your research and manufacturing goals.