The pharmaceutical industry constantly seeks novel compounds and efficient synthesis routes to develop life-saving medications. In this quest, specialized chemical intermediates play a pivotal role. 4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide (CAS 26475-62-7) stands out as a compound with significant potential, serving as a key building block for pharmaceutical manufacturers. Understanding its properties and how to efficiently buy pharmaceutical intermediates like this is crucial for R&D success.

Chemical Profile and Properties
4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide, with the chemical formula C6H13NO3S and CAS number 26475-62-7, is a heterocyclic organic compound. Its structure features a thiomorpholine ring oxidized to a sulfone, with a 2-hydroxyethyl group attached to the nitrogen atom. This unique combination of functional groups imparts specific reactivity, making it valuable in complex organic synthesis. Typically supplied as a white to light yellow or orange crystalline powder, its melting point ranges from 73-77 °C. High purity, often exceeding 98% by GC analysis, is a critical parameter for its use in sensitive pharmaceutical applications, ensuring the integrity and efficacy of the final drug product. As a chemical supplier, we prioritize delivering this purity.

Applications in Pharmaceutical Development
The primary application of 4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide is as an intermediate in the synthesis of Active Pharmaceutical Ingredients (APIs). Its structural features allow chemists to introduce specific functionalities or build complex molecular scaffolds required for targeted drug therapies. For instance, its ability to act as a nucleophile or a source of a particular functional group can be exploited in multi-step syntheses.

When researchers and development teams need to purchase raw materials for drug synthesis, reliable sources are paramount. A consistent supply of high-purity intermediates directly impacts the reproducibility and scalability of synthesis processes. As a dedicated manufacturer in China, we understand these demands and strive to provide chemical intermediates that meet stringent pharmaceutical quality standards.

Procurement Considerations for Pharmaceutical Manufacturers
For pharmaceutical companies looking to procure 4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide, several factors are essential:

  • Purity and Specifications: Always verify the purity (e.g., ≥98% GC) and request detailed specifications. Certificates of Analysis (CoA) are non-negotiable.
  • Supplier Reliability: Partner with experienced pharmaceutical intermediate suppliers who have a proven track record in quality, delivery, and compliance. A strong supply chain is critical for ongoing production.
  • Scalability: Ensure the supplier can scale up production to meet future demand as your drug candidate progresses through clinical trials. Companies offering capacities of 10+ tons are typically well-equipped.
  • Regulatory Support: Availability of documentation such as Safety Data Sheets (SDS) and adherence to GMP principles (where applicable) are vital for pharmaceutical manufacturing.

By carefully selecting a supplier and understanding the critical properties of this intermediate, pharmaceutical manufacturers can confidently integrate 4-(2-Hydroxyethyl)thiomorpholine 1,1-Dioxide into their synthesis pipelines, driving innovation and bringing new medicines to market.