In the intricate world of pharmaceutical research and development, the availability of versatile and high-quality chemical building blocks is essential. 4,6-Dichloro-2-methylpyrimidine (CAS: 1780-26-3) stands out as a pivotal intermediate, playing a significant role in the synthesis of numerous important therapeutic agents. As a dedicated pharmaceutical intermediate supplier, we understand the critical demands of researchers and manufacturers for reliable access to such compounds.

A Foundation for Innovative Therapies

The unique chemical structure of 4,6-Dichloro-2-methylpyrimidine, featuring a pyrimidine ring with strategically placed chlorine atoms, allows for diverse chemical modifications. This inherent reactivity makes it an invaluable starting material for complex organic synthesis. Its most prominent applications include its use as a key intermediate in the production of:

  • Dasatinib: A potent BCR-ABL and Src family tyrosine kinase inhibitor used in the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). The synthesis pathway critically relies on the precise chemical properties of this intermediate.
  • Moxonidine: An antihypertensive agent that acts as a centrally sympatholytic drug. Its development also incorporates this essential pyrimidine derivative.

Researchers are continually exploring derivatives of this compound for potential applications in other therapeutic areas, including anti-inflammatory agents and novel antibiotics, underscoring its broad utility. As a leading manufacturer of 4,6-dichloro-2-methylpyrimidine, we ensure that our product meets the high purity standards (≥99.0%) required for such advanced research and development.

Why Choose a Reliable Supplier?

For drug discovery teams, having a stable and trustworthy source for intermediates like 4,6-Dichloro-2-methylpyrimidine is crucial. Delays or inconsistencies in supply can significantly hamper research timelines and R&D budgets. When you decide to buy 4,6-dichloro-2-methylpyrimidine, partnering with a reputable supplier means not just acquiring a chemical, but gaining a reliable ally. Look for suppliers who offer:

  • Consistent Quality: Guaranteed high purity levels and rigorous quality control.
  • Scalable Production: The ability to provide quantities ranging from research-scale to commercial manufacturing needs.
  • Technical Expertise: Support and information regarding the compound's applications and handling.
  • Competitive Pricing: Cost-effectiveness without compromising on product integrity.

Our commitment as a premier 4,6-dichloro-2-methylpyrimidine supplier in China is to empower scientific innovation by providing the essential chemical tools. Whether you are synthesizing established drugs or exploring novel therapeutic avenues, we are here to support your mission with high-quality intermediates.