The Crucial Role of 4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide in Sildenafil Production
In the intricate world of pharmaceutical manufacturing, the quality and reliability of intermediate compounds are paramount. One such critical component is 4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide, a chemical entity that plays an indispensable role in the synthesis of Sildenafil citrate. As a key building block, its precise chemical structure and high purity directly influence the efficacy and safety of the final active pharmaceutical ingredient (API). Understanding the properties and applications of this pyrazole derivative is essential for manufacturers seeking to produce Sildenafil, a medication widely used to treat erectile dysfunction and pulmonary arterial hypertension.
The compound, commonly identified by its CAS number 139756-02-8, presents itself as a white powder. This physical characteristic, coupled with stringent purity standards often exceeding 99%, makes it highly suitable for industrial chemical synthesis. Manufacturers rely on such intermediates to ensure that their downstream processes yield the desired product with minimal impurities. The consistent quality of 4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide is a testament to the advanced manufacturing capabilities and quality control measures employed by its producers. Sourcing this intermediate from reputable 4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide manufacturers in China has become a common practice for global pharmaceutical companies, given the region's expertise in fine chemical production.
Beyond its primary role in Sildenafil synthesis, research has also highlighted the potential of 4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide as a hypolipidemic agent, suggesting its utility in managing lipid levels, and as a possible phosphodiesterase 1 (PDE1) inhibitor. These additional potential applications underscore its significance in drug discovery and development, positioning it not just as an intermediate but also as a molecule of interest for novel therapeutic interventions. For companies looking to purchase 4-Amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide, ensuring a stable supply chain and competitive pricing is crucial for maintaining production efficiency.
The handling and storage of this compound require adherence to specific guidelines to preserve its chemical integrity. Recommendations typically include storing it in a cool, dry environment, often at -20°C, to prevent degradation from moisture or heat. This meticulous approach to storage is a critical aspect of pharmaceutical intermediate management, ensuring that the compound remains viable for its intended purpose. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent supplier that emphasizes quality and reliability in its product offerings, making them a trusted partner for those in need of this vital chemical.
Perspectives & Insights
Logic Thinker AI
“As a key building block, its precise chemical structure and high purity directly influence the efficacy and safety of the final active pharmaceutical ingredient (API).”
Molecule Spark 2025
“Understanding the properties and applications of this pyrazole derivative is essential for manufacturers seeking to produce Sildenafil, a medication widely used to treat erectile dysfunction and pulmonary arterial hypertension.”
Alpha Pioneer 01
“The compound, commonly identified by its CAS number 139756-02-8, presents itself as a white powder.”