The relentless pursuit of novel therapeutics in the pharmaceutical industry relies heavily on the availability of versatile chemical building blocks. 4-Bromo-2-(trifluoromethyl)benzonitrile (CAS: 191165-13-6) has emerged as a compound of significant interest for drug discovery programs due to its strategic functional groups. For researchers in this field, knowing where and how to buy 4-bromo-2-(trifluoromethyl)benzonitrile intermediate is crucial for advancing their projects.

Incorporating Trifluoromethyl Groups in Pharmaceuticals

The trifluoromethyl (-CF3) group is a highly sought-after moiety in medicinal chemistry. Its incorporation into drug molecules can dramatically influence their properties, often leading to enhanced metabolic stability, increased lipophilicity, and improved binding affinity to target proteins. 4-Bromo-2-(trifluoromethyl)benzonitrile provides a convenient way to introduce this valuable functional group, along with a reactive bromine atom for further elaboration.

Synthetic Pathways and Applications

The primary application of this compound as a pharmaceutical intermediate is in the synthesis of downstream molecules that are integral to drug candidates. For instance, it serves as a precursor for compounds used in oncology, antivirals, and CNS-acting agents. The bromine atom on the aromatic ring is an excellent handle for palladium-catalyzed cross-coupling reactions, allowing for the efficient construction of complex molecular architectures commonly found in active pharmaceutical ingredients (APIs). This makes it a key component for organic synthesis that aims for therapeutic innovation.

When seeking this vital intermediate, it is essential to partner with a reliable 4-bromo-2-(trifluoromethyl)benzonitrile supplier in China. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. are equipped to provide the high purity (often 98%) required for pharmaceutical research. The cas 191165-13-6 price offered by such direct suppliers is typically competitive, supporting the often budget-constrained nature of drug discovery. Moreover, the availability of custom synthesis options can be invaluable for unique research needs.

Ensuring Quality and Supply Chain Integrity

For drug discovery teams, the integrity of the supply chain and the consistent quality of intermediates are paramount. Engaging with an established organic synthesis intermediate manufacturer ensures that the compound meets stringent pharmaceutical standards. Requesting a free sample allows for thorough in-house validation, giving researchers confidence in their chosen chemical partner. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing the high-quality intermediates that power the next generation of medicines.