Organic chemists constantly seek versatile building blocks to unlock new synthetic pathways and create novel molecules. Among these essential reagents is 4-Bromothiophenol (CAS 106-53-6), a compound that offers significant utility due to its unique chemical structure. As a dedicated supplier of fine chemicals, we understand the importance of this material for researchers and manufacturers alike. This article delves into the applications of 4-Bromothiophenol in organic synthesis and provides insights on how to procure it effectively.

4-Bromothiophenol: A Foundation for Molecular Innovation

4-Bromothiophenol, with its CAS number 106-53-6, is an aromatic thiol featuring a bromine atom at the para position. This dual functionality – the reactive thiol group and the versatile bromine atom – makes it a highly sought-after intermediate in a wide array of organic transformations. Typically available as a white to yellow crystalline powder, its chemical properties, including a melting point of 73-76°C and a boiling point of 239°C, are well-documented.

The compound is a key starting material for numerous reactions:

  • Thiol Reactions: The thiol (-SH) group readily participates in S-alkylation, S-acylation, and Michael additions, allowing for the introduction of sulfur-containing functionalities into target molecules. This is critical for synthesizing heterocycles, thioethers, and other organosulfur compounds.
  • Aromatic Substitution: The bromine atom on the benzene ring can be utilized in various palladium-catalyzed cross-coupling reactions, such as Suzuki, Sonogashira, and Heck couplings. These reactions enable the formation of carbon-carbon or carbon-heteroatom bonds, expanding the complexity of the synthesized molecules.
  • Synthesis of Heterocyclic Compounds: 4-Bromothiophenol is instrumental in constructing various heterocyclic systems, which are prevalent in pharmaceuticals, agrochemicals, and materials science. Its incorporation often leads to compounds with unique biological activities or material properties.

Procurement for Your Research and Development

For chemists and researchers looking to buy 4-Bromothiophenol, several factors are crucial for successful procurement. As a reputable chemical manufacturer and supplier based in China, we prioritize delivering high-quality materials with a clear focus on customer needs.

  • Supplier Selection: Choosing a supplier with expertise in fine chemicals and organic intermediates is vital. We offer 4-Bromothiophenol with a guaranteed minimum purity of 97%, suitable for rigorous synthetic procedures.
  • Requesting Samples and Quotes: We encourage researchers to request samples to verify product quality and consistency. Obtaining a formal quote allows for price comparisons and budget planning. Mentioning your specific application, such as synthesis of thiophene derivatives or cross-coupling reactions, can help us tailor our offering.
  • Understanding Specifications: Always confirm the CAS number (106-53-6) and the listed physical and chemical properties. This ensures you are procuring the correct reagent for your intended reaction conditions.
  • Technical Support: Don't hesitate to reach out for technical assistance. Understanding the reactivity and handling precautions of 4-Bromothiophenol can enhance your experimental success and safety.

We are committed to supporting the scientific community by providing essential chemical building blocks. Whether you are a research scientist developing a novel synthetic route or a production manager scaling up a process, our goal is to be your reliable source for 4-Bromothiophenol. Contact us today to learn more about our product offerings and how we can assist your chemical synthesis projects.