The pharmaceutical industry relies heavily on a consistent supply of high-quality chemical intermediates to drive innovation and production. Among these, 4-Hydroxyacetophenone (CAS 99-93-4) stands out for its critical role in synthesizing a wide range of active pharmaceutical ingredients (APIs). For pharmaceutical manufacturers and R&D scientists, understanding the utility and sourcing of this compound is vital for successful drug development and commercialization.

4-Hydroxyacetophenone: A Key Pharmaceutical Intermediate

4-Hydroxyacetophenone, chemically known as 4-acetylphenol, is a phenolic ketone that serves as a foundational building block in complex organic synthesis. Its molecular structure, featuring both a hydroxyl and a carbonyl group, allows for a multitude of chemical reactions, making it a versatile intermediate for crafting sophisticated drug molecules. The requirement for high purity, often 99% or more, is non-negotiable in this sector to ensure the efficacy, safety, and regulatory compliance of the final drug products.

Applications in Drug Synthesis

The primary utility of 4-Hydroxyacetophenone in pharmaceuticals lies in its function as an intermediate for:

  • Cardiovascular Drugs: It is a precursor in the synthesis of various medications designed to treat heart conditions and circulatory system disorders.
  • Nervous System Medications: Its structure is incorporated into compounds used to treat neurological and psychological conditions.
  • Analgesics and Antipyretics: It can be a starting material for producing pain relievers and fever reducers.
  • Antimicrobial Agents: Its chemical properties lend themselves to the synthesis of compounds with antibacterial or antifungal activity.

Procuring 4-Hydroxyacetophenone from a reputable manufacturer is paramount. Pharmaceutical companies must source materials that meet stringent quality control standards. A reliable supplier, particularly one based in China, can offer competitive pricing and a stable supply chain, ensuring that production lines remain uninterrupted and research projects stay on track. When you are looking to buy this intermediate, always inquire about the purity levels and any available certifications.

Ensuring Quality and Compliance for Pharmaceutical Use

For pharmaceutical applications, sourcing 4-Hydroxyacetophenone involves more than just finding a low price. Key considerations include:

  • Purity Levels: Verify that the product meets the required purity (e.g., 99%min) with detailed Certificates of Analysis (CoA).
  • Manufacturing Standards: While not always requiring GMP for intermediates, understanding the manufacturer's quality control processes is beneficial.
  • Regulatory Compliance: Ensure the supplier can provide necessary documentation for regulatory submissions.
  • Supply Chain Stability: Partnering with a manufacturer that has a robust production capacity and efficient logistics is crucial for uninterrupted supply.

As a B2B procurement specialist, focusing on the long-term value of a consistent, high-quality supply of 4-Hydroxyacetophenone from a trusted manufacturer in China will yield better results than prioritizing short-term cost savings alone. This approach supports not only your current manufacturing needs but also future product development pipelines.