In the dynamic field of pharmaceutical research and development, the availability of highly specialized chemical intermediates is crucial for scientific advancement. 4-Hydroxybenzamidine Hydrochloride (CAS 38148-63-9) is one such compound, playing a significant role in various research applications, particularly in the study of enzyme kinetics and the development of novel therapeutic agents.

Enzyme Inhibition and Protease Studies
One of the most recognized applications of 4-Hydroxybenzamidine Hydrochloride is its function as an inhibitor of serine proteases. These enzymes are critical in numerous biological pathways, and their dysregulation is implicated in various diseases. Researchers utilize this compound in laboratory settings to study the mechanisms of these enzymes, understand their role in disease pathogenesis, and screen for new drug candidates that can modulate their activity. The specific structure of 4-Hydroxybenzamidine Hydrochloride allows it to bind effectively to the active sites of certain proteases, providing valuable insights into enzyme function.

A Building Block for Drug Discovery
Beyond its direct use in enzymatic studies, 4-Hydroxybenzamidine Hydrochloride serves as a key intermediate in the synthesis of more complex pharmaceutical compounds. Its hydroxyl group and amidine functionality provide reactive sites that medicinal chemists can leverage to build diverse molecular structures. This makes it an important starting material or intermediate in the multi-step synthesis of potential drugs targeting a range of conditions. Its consistent availability from reliable chemical manufacturers is essential for the continuity of these drug discovery programs.

Quality and Sourcing for Research
For any pharmaceutical research, the quality and purity of chemical reagents are paramount. 4-Hydroxybenzamidine Hydrochloride, when sourced from reputable chemical suppliers, typically comes with a high purity guarantee (e.g., ≥99% via HPLC). This ensures that experimental results are accurate and reproducible. Researchers and procurement teams often look for suppliers who can provide comprehensive documentation, including CoAs and SDSs, and who can offer the material in quantities suitable for both bench-scale experiments and pilot studies. The ability to purchase from a trustworthy manufacturer or distributor ensures that the integrity of the research is maintained from the outset.

In summary, 4-Hydroxybenzamidine Hydrochloride is more than just a chemical; it is an enabler of scientific progress in the pharmaceutical sector. Its role as an enzyme inhibitor and a versatile synthetic intermediate underscores its importance in the ongoing quest for new and effective medicines.