Organic synthesis is the backbone of innovation in fields ranging from pharmaceuticals to material science. At the heart of this discipline are versatile chemical intermediates that enable the creation of complex molecular architectures. 5-Fluoro-2-iodotoluene, characterized by CAS number 28490-56-4, is one such compound that has gained significant traction due to its unique reactivity and structural features. As a key organic intermediate, understanding its role and applications is vital for chemists and procurement specialists alike.

The presence of both a fluorine atom and an iodine atom on a toluene ring endows 5-Fluoro-2-iodotoluene with exceptional synthetic utility. The fluorine atom often imparts desirable properties such as increased lipophilicity, metabolic stability, and enhanced binding affinity in biologically active molecules. The iodine atom, on the other hand, serves as an excellent leaving group and is highly amenable to a variety of metal-catalyzed cross-coupling reactions. This makes it a prime candidate for Suzuki, Stille, Negishi, and other C-C bond-forming reactions, allowing for the efficient introduction of diverse substituents. For those looking to buy 5-Fluoro-2-iodotoluene, accessing this compound with high purity (≥98%) from a reliable supplier is crucial for successful synthetic outcomes.

In pharmaceutical synthesis, this intermediate is invaluable for constructing fluorinated aromatic systems commonly found in many drug molecules. Its use in creating complex heterocyclic compounds and functionalized aromatic rings contributes to the development of new therapeutic agents. Similarly, in the agrochemical industry, it acts as a building block for creating novel pesticides and plant growth regulators. Procurement professionals seeking to optimize their supply chain can benefit from sourcing this material from dedicated manufacturers in China, often securing a favorable CAS 28490-56-4 price.

The physical characteristics of 5-Fluoro-2-iodotoluene—a brown liquid with a density of 1.788 g/cm³ and a boiling point of 206.8ºC—are also important for chemists to consider during reaction planning and execution. Its typical availability in 25kg drums from NINGBO INNO PHARMCHEM CO.,LTD. ensures convenient handling for laboratory research and industrial-scale production. When you purchase 5-Fluoro-2-iodotoluene, you are investing in a versatile tool for chemical innovation.

In summary, 5-Fluoro-2-iodotoluene is a powerful intermediate in modern organic synthesis, facilitating the creation of complex molecules essential for pharmaceuticals and agrochemicals. Its strategic importance highlights the need for reliable sourcing from quality manufacturers and suppliers.