In the dynamic field of organic synthesis, access to unique and versatile chemical building blocks is crucial for innovation. 5-Methoxy-1H-pyrrolo[2,3-b]pyridine, known by its CAS number 183208-36-8, has emerged as a significant intermediate for researchers and chemists engaged in complex synthetic endeavors. This article delves into the applications and advantages of this heterocyclic compound, particularly for R&D professionals seeking high-quality materials from reliable global suppliers.

Chemical Profile and Significance

5-Methoxy-1H-pyrrolo[2,3-b]pyridine, with the molecular formula C8H8N2O and a molecular weight of 148.16, is a derivative of 7-azaindole. Its structure features a pyrrolo[2,3-b]pyridine core with a methoxy group at the 5-position. This specific arrangement of functional groups makes it an attractive starting material or intermediate in the synthesis of a wide array of bioactive molecules. Its physical state is typically described as a tan solid, and it is often available with purities of 95% or higher, making it suitable for sensitive reaction chemistries.

Applications in Research and Development

The primary utility of 5-Methoxy-1H-pyrrolo[2,3-b]pyridine lies in its role as a versatile synthon. R&D chemists utilize it in:

  • Drug Discovery: As a core scaffold for designing novel drug candidates, particularly in areas targeting kinases, G-protein coupled receptors, and other biological targets.
  • Medicinal Chemistry: Modifying its structure allows for the exploration of structure-activity relationships (SAR) in the development of new therapeutic agents.
  • Material Science: Its unique electronic and structural properties may also find applications in the development of new functional materials, although its primary use remains pharmaceutical.

When researching where to buy this compound, it's essential to consider suppliers who can provide not just the chemical itself, but also the necessary technical documentation and support.

Choosing a Supplier for Your Synthesis Needs

For chemists and research institutions, sourcing high-quality 5-Methoxy-1H-pyrrolo[2,3-b]pyridine is critical for reproducible and successful synthesis. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier, dedicated to providing top-tier chemicals. We understand the importance of purity and consistency in advanced organic synthesis. If you are looking to purchase this intermediate or require a custom synthesis service, our team is ready to assist. We offer competitive pricing and ensure that our products meet the rigorous standards expected by the research community. Partner with us to secure a reliable supply chain for your ongoing synthetic projects and accelerate your discovery pipeline.