In the realm of advanced organic synthesis, specific chemical intermediates play pivotal roles in unlocking new molecular architectures and functional materials. Among these, 6-Chloro-2-methyl-3-nitropyridine (CAS 22280-60-0) stands out as a versatile building block. For R&D scientists and product formulators, understanding its chemical properties and application potential is key to leveraging its full value. This article delves into the significance of this compound and how to acquire it from reliable suppliers.

Chemical Profile of 6-Chloro-2-methyl-3-nitropyridine

6-Chloro-2-methyl-3-nitropyridine is a heterocyclic aromatic compound belonging to the pyridine family. It typically presents as a light beige to brown crystalline powder, with a reported melting point range of 54-58°C. Its molecular formula is C6H5ClN2O2, and its molecular weight is approximately 172.57 g/mol. The presence of the chlorine atom and the nitro group on the pyridine ring makes it highly reactive and amenable to a variety of chemical transformations. This reactivity is what makes it a sought-after intermediate in complex synthetic routes.

Synthesis Pathways and Applications

The synthesis of 6-Chloro-2-methyl-3-nitropyridine often involves chlorination reactions on substituted pyridines. For instance, one common preparation method involves treating 2-oxo-5-nitro-6-methyl-1,2-dihydropyridine with phosphorus oxychloride and pentachloride. The resulting product can then be further utilized in various synthetic schemes. Its primary application lies in its role as a precursor for more complex molecules. Researchers have used it to synthesize fluorine-containing pyridinealdoxime derivatives, demonstrating its utility in medicinal chemistry and the development of potential therapeutic agents.

Sourcing this Intermediate: Manufacturer Advantages

For procurement professionals and R&D teams, sourcing high-quality 6-Chloro-2-methyl-3-nitropyridine is essential. Leading chemical manufacturers in China specialize in producing this intermediate with high purity (often 98% GC or higher). When you buy this compound, partnering with a manufacturer ensures not only competitive pricing but also consistent quality and reliable supply. These suppliers understand the stringent requirements of the R&D sector and are equipped to provide necessary documentation, such as COAs, to support your product validation processes.

Why Choose a Reputable Supplier?

The integrity of your research and development efforts hinges on the quality of the starting materials. A reliable manufacturer of 6-Chloro-2-methyl-3-nitropyridine will adhere to strict quality control measures throughout the production process. This includes ensuring accurate product specifications, proper handling, and secure packaging to maintain product integrity during transit. Furthermore, experienced suppliers can often provide technical support and ensure compliance with international shipping regulations. When you consider purchasing this chemical, always prioritize suppliers who can demonstrate a strong commitment to quality assurance and customer service.

In conclusion, 6-Chloro-2-methyl-3-nitropyridine is a compound of significant interest for its synthetic versatility. By understanding its properties and engaging with reputable manufacturers and suppliers, researchers and formulators can effectively obtain this crucial intermediate to advance their projects.