The Role of 7-Bromo-4-fluoroindole in Advanced Organic Synthesis
In the intricate world of organic synthesis, specific molecular structures serve as foundational elements for creating complex compounds. 7-Bromo-4-fluoroindole, identified by CAS number 292636-09-0, stands out as a highly valuable heterocyclic intermediate. Its unique combination of a bromo substituent, a fluoro substituent, and an indole core makes it an indispensable tool for synthetic chemists aiming to build novel molecules, particularly in the pharmaceutical sector.
As a pharmaceutical raw intermediate, 7-Bromo-4-fluoroindole offers multiple reaction sites. The bromine atom can readily participate in cross-coupling reactions, such as Suzuki, Sonogashira, or Buchwald-Hartwig couplings, allowing for the introduction of diverse organic fragments. The fluorine atom, with its high electronegativity, can influence the electronic properties and metabolic stability of the final synthesized drug molecule, often leading to improved pharmacokinetic profiles. The indole scaffold itself is a privileged structure found in numerous biologically active compounds and natural products.
For researchers and product formulators, understanding the applications of this compound is crucial when deciding to buy. 7-Bromo-4-fluoroindole is instrumental in the synthesis of various pharmaceutical candidates targeting a range of therapeutic areas. Its utility extends to materials science as well, where functionalized indole derivatives can be explored for their electronic or optical properties.
When sourcing this essential intermediate, partnering with a reliable China manufacturer like ourselves ensures access to materials with consistent high purity, typically 97% minimum. This quality is vital for reproducible synthetic outcomes. We aim to provide a stable supply of 7-Bromo-4-fluoroindole, supporting your R&D efforts from laboratory scale to pilot production. Explore the possibilities this versatile building block offers for your next synthetic challenge.
Perspectives & Insights
Future Origin 2025
“Its unique combination of a bromo substituent, a fluoro substituent, and an indole core makes it an indispensable tool for synthetic chemists aiming to build novel molecules, particularly in the pharmaceutical sector.”
Core Analyst 01
“As a pharmaceutical raw intermediate, 7-Bromo-4-fluoroindole offers multiple reaction sites.”
Silicon Seeker One
“The bromine atom can readily participate in cross-coupling reactions, such as Suzuki, Sonogashira, or Buchwald-Hartwig couplings, allowing for the introduction of diverse organic fragments.”