The intricate world of chemical synthesis demands precise building blocks that enable the creation of complex molecules with specific functionalities. 8-Bromo-3-methylxanthine (CAS 93703-24-3) is one such intermediate, valued for its unique chemical structure and reactivity, making it indispensable in advanced organic synthesis, particularly within the pharmaceutical sector. This article explores its chemical properties and its significant role in modern synthesis.

8-Bromo-3-methylxanthine is a derivative of xanthine, a purine base. Its chemical formula is C6H5BrN4O2, and it possesses a molecular weight of approximately 245.03 g/mol. Key chemical properties include its appearance as a white to almost white powder and a high melting point, typically above 300°C, indicating thermal stability. The presence of the bromine atom at the 8-position of the xanthine ring system is crucial, as it serves as a reactive site for various substitution and coupling reactions commonly employed in medicinal chemistry.

The primary application of 8-Bromo-3-methylxanthine is as a pharmaceutical intermediate. Its most notable use is in the multi-step synthesis of Linagliptin, a selective DPP-4 inhibitor. The bromo substituent allows for the facile introduction of other functional groups through reactions such as Suzuki or Buchwald-Hartwig couplings, enabling the construction of the complex molecular architecture of Linagliptin. This makes it a valuable compound for researchers and manufacturers focused on developing novel therapeutics.

For chemists engaged in R&D, understanding the reactivity profile of 8-Bromo-3-methylxanthine is key. It can undergo nucleophilic substitution reactions, and its purine core makes it amenable to various functionalization strategies. When you buy 8-Bromo-3-methylxanthine, ensuring high purity from a reputable supplier is essential to achieve predictable and reproducible results in your synthesis. We are a leading manufacturer and supplier of this intermediate, committed to providing materials that meet stringent quality standards, thereby supporting your most demanding chemical synthesis projects.

In conclusion, 8-Bromo-3-methylxanthine is more than just a chemical; it's a strategic tool for chemists pushing the boundaries of molecular design. Its utility in synthesizing important APIs underscores its significance. If you are looking for a reliable source to purchase this compound, consider our offerings. We provide high-purity 8-Bromo-3-methylxanthine, backed by comprehensive technical data and a commitment to supporting the advancements in chemical synthesis. Request a quote to explore how we can assist your research and production needs.