In the relentless pursuit of effective treatments for viral infections, the synthesis of complex pharmaceutical compounds relies heavily on specialized chemical intermediates. Among these, (1S,4R)-4-Amino-2-cyclopentene-1-methanol D-hydrogen tatrate (CAS 229177-52-0) stands out as a critical component, particularly in the production of antiviral medications. This article delves into the chemical and pharmaceutical importance of this compound, guiding R&D scientists and procurement specialists on its role and how to source it effectively.

Chemical Identity and Pharmaceutical Importance

The compound, (1S,4R)-4-Amino-2-cyclopentene-1-methanol D-hydrogen tatrate, is a white solid characterized by its specific stereochemistry. Its primary application is as an intermediate in the synthesis of Abacavir, a potent nucleoside analog used in antiretroviral therapy for HIV/AIDS. The precise molecular structure and chirality are essential for Abacavir's pharmacological activity, enabling it to inhibit the reverse transcriptase enzyme of the human immunodeficiency virus. Manufacturers producing this intermediate must therefore maintain stringent control over enantiomeric purity to ensure the final drug's safety and efficacy.

Synthesis and Manufacturing Insights

The synthesis of (1S,4R)-4-Amino-2-cyclopentene-1-methanol D-hydrogen tatrate involves sophisticated chemical processes. Typically, the synthesis starts with precursors that are cyclized to form the cyclopentene ring, followed by stereoselective amination. The final step involves salt formation with D-tartaric acid to yield the tartrate salt, which enhances stability and handling properties. For bulk purchase, understanding the manufacturing capabilities of potential suppliers is vital. Factors such as yield, reaction conditions, purification methods, and adherence to quality standards are key indicators of a reliable manufacturer. Companies like NINGBO INNO PHARMCHEM CO.,LTD. focus on optimizing these processes to deliver high-purity intermediates.

Why You Should Buy from a Specialized Manufacturer

Procuring essential pharmaceutical intermediates like this requires more than just a simple transaction; it necessitates a partnership with a dependable supplier. When you decide to buy this intermediate, consider the following benefits of working with a specialized manufacturer:

  • Guaranteed Purity: Direct manufacturers often have more robust quality control systems, ensuring the product meets the strict purity requirements (≥99.0%) needed for API synthesis.
  • Technical Support: Manufacturers can often provide detailed technical data, safety information (SDS), and support for your R&D or production queries.
  • Competitive Pricing: By cutting out intermediaries, you can achieve more competitive pricing for bulk orders, contributing to the overall cost-effectiveness of your drug development.
  • Supply Chain Security: A reliable manufacturer can offer a secure and consistent supply chain, crucial for managing production timelines and avoiding costly delays.

The global demand for effective antiviral treatments underscores the importance of consistent access to high-quality intermediates. By choosing NINGBO INNO PHARMCHEM CO.,LTD. as your supplier, you align with a manufacturer dedicated to pharmaceutical quality and supply chain integrity.

In summary, (1S,4R)-4-Amino-2-cyclopentene-1-methanol D-hydrogen tatrate is more than just a chemical compound; it's a critical building block for modern medicine. Its successful synthesis and availability are a testament to the chemical industry's role in public health. If your organization requires this intermediate, exploring options with experienced manufacturers in China is a prudent step toward securing a reliable and high-quality source.