The Role of Boc-L-4-Methoxyphenylalanine in Pharmaceutical Development
The journey from scientific concept to a marketable pharmaceutical product is intricate, relying on a foundation of high-quality chemical intermediates. Among these, Boc-L-4-Methoxyphenylalanine, bearing the CAS number 53267-93-9, plays a significant role, particularly in the development of peptide-based therapeutics and novel drug candidates. For research scientists and procurement managers, understanding the utility and sourcing of this key compound is vital for driving innovation.
Boc-L-4-Methoxyphenylalanine is a protected amino acid, characterized by the tert-butoxycarbonyl (Boc) group attached to its amino nitrogen. This protecting group is a cornerstone of modern organic synthesis, especially in peptide chemistry. It allows for the controlled assembly of peptide chains by preventing unintended reactions at the amino terminus, ensuring that synthesis proceeds regioselectively. The specific structure of Boc-L-4-Methoxyphenylalanine, with its 4-methoxy substitution on the phenyl ring, offers unique steric and electronic properties that can be exploited to fine-tune the conformational and binding characteristics of target peptides.
Its primary application lies in peptide synthesis, where it serves as a fundamental building block for incorporating a modified tyrosine residue into complex peptide sequences. This is crucial for creating peptides with enhanced biological activity, improved stability against degradation, or tailored pharmacokinetic profiles. In the broader scope of pharmaceutical development, this compound is instrumental in the synthesis of potential drug molecules, acting as a versatile intermediate in the creation of enzyme inhibitors, receptor agonists, antagonists, and other biologically active agents. Its high purity, typically 97%, is critical for the success of these intricate synthetic processes.
For professionals in the pharmaceutical industry, securing a reliable supply of Boc-L-4-Methoxyphenylalanine is essential. When looking to buy this compound, especially in bulk quantities, partnering with experienced manufacturers and suppliers is key. Companies specializing in fine chemical synthesis, particularly those based in China, often provide competitive pricing and consistent product quality. Prioritizing a supplier that can offer detailed technical documentation, such as Certificates of Analysis (CoA) and Safety Data Sheets (SDS), is crucial for quality assurance and safe laboratory practices.
The demand for sophisticated peptide-based drugs continues to grow, underscoring the importance of intermediates like Boc-L-4-Methoxyphenylalanine. By ensuring a high-quality, consistent supply from trusted sources, pharmaceutical companies can accelerate their research and development timelines, ultimately bringing innovative treatments to patients more efficiently.
Perspectives & Insights
Future Origin 2025
“The journey from scientific concept to a marketable pharmaceutical product is intricate, relying on a foundation of high-quality chemical intermediates.”
Core Analyst 01
“Among these, Boc-L-4-Methoxyphenylalanine, bearing the CAS number 53267-93-9, plays a significant role, particularly in the development of peptide-based therapeutics and novel drug candidates.”
Silicon Seeker One
“For research scientists and procurement managers, understanding the utility and sourcing of this key compound is vital for driving innovation.”