The field of organic chemistry has witnessed remarkable advancements, with new synthetic methodologies continually emerging to facilitate the creation of complex molecules. Among these, reactions involving organoboron compounds, particularly boronic esters, have become indispensable tools in modern pharmaceutical synthesis. These compounds are prized for their versatility and reactivity, especially in carbon-carbon bond formation reactions like the Suzuki-Miyaura coupling. A prominent example showcasing the utility of boronic esters is tert-Butyl (2S)-2-[5-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazol-2-yl]pyrrolidine-1-carboxylate (CAS: 1007882-12-3).

This compound, a key intermediate in the synthesis of the antiviral drug Daclatasvir, features a phenylboronic ester moiety. The 4,4,5,5-tetramethyl-1,3,2-dioxaborolane group is a stable yet reactive boronic ester that readily participates in palladium-catalyzed cross-coupling reactions. This allows for the precise attachment of the phenyl ring to other molecular fragments, a critical step in constructing the complex architecture of Daclatasvir. For pharmaceutical manufacturers, sourcing intermediates with well-defined boronic ester functionalities is essential for efficient and high-yield synthesis.

NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier specializing in advanced pharmaceutical intermediates, including those with sophisticated boronic ester chemistry. Our production of tert-Butyl (2S)-2-[5-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazol-2-yl]pyrrolidine-1-carboxylate ensures a high purity assay (≥98.0%), critical for the successful execution of Suzuki-Miyaura couplings and other related synthetic transformations. We understand the intricacies of handling and producing such sensitive reagents and are committed to providing our clients with reliable materials.

Researchers and procurement managers often search for terms related to 'buy boronic ester intermediates' or 'pharmaceutical synthesis reagents'. Our company offers a comprehensive range of such compounds, backed by competitive prices and a commitment to quality. As a prominent supplier in China, we aim to simplify the procurement process for these specialized chemicals. If you are looking to purchase high-quality tert-Butyl (2S)-2-[5-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1H-imidazol-2-yl]pyrrolidine-1-carboxylate or other advanced organic synthesis intermediates, we invite you to contact us for a quote and further information.