Peptide synthesis is a cornerstone of modern biotechnology and pharmaceuticals, enabling the creation of therapeutic agents, research tools, and novel materials. The efficiency and success of these complex processes often hinge on the quality and purity of the starting materials. Among these, N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester (CAS 117833-18-8) stands out as a crucial intermediate, valued for its specific chemical structure and high purity.

What is N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester?

N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester, identified by CAS number 117833-18-8, is a derivative of aspartic acid. It features an N-acetyl group and a tert-butyl ester protection on the beta-carboxyl group. This specific structure makes it an invaluable protected amino acid building block for solid-phase peptide synthesis (SPPS) and solution-phase peptide synthesis.

Key Applications in Peptide Synthesis

The tert-butyl ester group serves as a common protecting group for the carboxylic acid functionality of amino acids. Its stability under typical coupling conditions and its facile removal under acidic conditions make it highly advantageous in peptide synthesis. N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester allows for the controlled introduction of modified aspartic acid residues into a growing peptide chain, enabling the synthesis of peptides with specific biological activities or structural properties.

Researchers often need to buy this intermediate to create peptides that are used in drug discovery, diagnostics, and as biochemical probes. The ability to reliably purchase this compound, often from specialized suppliers, ensures that research and development projects can proceed without interruption. The quality, particularly the assay of 99% min, is critical for preventing side reactions and ensuring the purity of the synthesized peptide.

The Importance of Purity and Supplier Reliability

For effective peptide synthesis, the purity of intermediates like CAS 117833-18-8 cannot be overstated. Impurities can lead to truncated sequences, undesired side products, and significantly lower yields, complicating purification and increasing overall costs. Therefore, sourcing from reputable manufacturers and suppliers who guarantee high purity is essential. When you are looking to buy this compound, prioritizing suppliers with stringent quality control measures ensures the integrity of your synthesis efforts.

Procurement and Commercial Considerations

When procuring N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester, consider factors such as packaging (e.g., 25kg drums), minimum order quantities, and pricing. Experienced suppliers can provide detailed technical data sheets (TDS) and safety data sheets (SDS) to support your evaluation. For those needing to purchase, understanding the manufacturer's capabilities and their position as a reliable supplier in regions like China can streamline the procurement process.

In summary, N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester (CAS 117833-18-8) plays a vital role in the field of peptide synthesis. Its specific protective group strategy and high purity make it a sought-after building block. Ensuring a consistent supply of this intermediate from a trusted manufacturer is key to advancing research and development in biochemistry and pharmaceuticals.