In the intricate world of chemical synthesis, specific compounds act as linchpins, enabling complex molecular construction. N-(Diphenylmethylene)glycine tert-butyl ester, bearing the CAS number 81477-94-3, is one such vital intermediate. Its unique chemical properties and availability make it a sought-after material for researchers and manufacturers alike. Understanding the role of CAS 81477-94-3 in modern chemical synthesis is key to leveraging its full potential.

This compound, often supplied as a white crystalline powder, is an ester derivative of glycine, featuring a tert-butyl group and a diphenylmethylene moiety. Its structural attributes lend themselves to a variety of synthetic transformations. Typically, the purity offered by manufacturers is 97% or higher, ensuring that the compound is suitable for sensitive reactions where impurity control is critical. The stability and ease of handling of this material also contribute to its widespread adoption in laboratories and industrial settings.

The primary applications of N-(Diphenylmethylene)glycine tert-butyl ester (CAS 81477-94-3) are deeply rooted in its utility as a versatile building block. In pharmaceutical development, it serves as an essential intermediate for synthesizing various active pharmaceutical ingredients (APIs). Its structure can be manipulated to introduce specific functional groups or to form key backbone structures in complex drug molecules. The tert-butyl ester group often acts as a protecting group, which can be selectively removed later in the synthetic sequence. This makes it invaluable for multi-step syntheses common in drug discovery.

Furthermore, this chemical intermediate finds application in agrochemical research, contributing to the development of new pesticides, herbicides, and fungicides. Its structural features can be modified to create compounds with targeted biological activity against pests or weeds, while minimizing environmental impact. For academic institutions and contract research organizations (CROs), sourcing this compound for experimental purposes is straightforward, with many suppliers offering research-grade quantities. When seeking to buy CAS 81477-94-3, looking for manufacturers with a strong quality control system is paramount.

The commercial availability of N-(Diphenylmethylene)glycine tert-butyl ester is supported by a global network of chemical suppliers. For businesses operating in North America, Europe, and Asia, identifying a reliable supplier that can offer consistent quality and competitive pricing is a strategic imperative. Many Chinese manufacturers are recognized for their expertise in producing fine chemical intermediates like CAS 81477-94-3, offering advantages in terms of both cost and scale. When you choose a manufacturer, consider their production capacity, lead times for orders, and customer support services. Securing a dependable source for this key intermediate is a critical step in streamlining your synthesis operations and ensuring project success.