In the rigorous landscape of pharmaceutical development, chemical intermediates play a foundational role, enabling the synthesis of complex molecules that form the basis of life-saving medications. Dimethyl 1,3-acetonedicarboxylate, identified by its CAS number 1830-54-2, is a key intermediate with significant utility in this sector. Its unique chemical structure and reactivity make it an invaluable component for researchers and manufacturers aiming to develop new drugs and therapies. For procurement managers and scientists, understanding the compound's properties and ensuring a reliable supply chain are critical for project success.

Dimethyl 1,3-acetonedicarboxylate is typically supplied as a clear, colorless to light yellow liquid, boasting a high assay of 98% minimum. This purity level is paramount in pharmaceutical synthesis, where even minor impurities can have significant impacts on reaction outcomes and the safety profile of the final product. The compound’s molecular formula is C7H10O5, with a molecular weight of 174.15. Its physical properties, such as a relatively low melting point (16-17°C) and a boiling point suitable for distillation under reduced pressure, facilitate its handling and purification in industrial settings. As a leading chemical manufacturer, we ensure these specifications are consistently met.

The primary application of Dimethyl 1,3-acetonedicarboxylate within the pharmaceutical industry is its function as a versatile intermediate. It serves as a crucial building block for synthesizing a variety of active pharmaceutical ingredients (APIs). Its reactive methylene group and ester functionalities allow it to participate in a wide range of synthetic transformations, including Knoevenagel condensations and Michael additions, which are commonly employed in drug discovery. Its use in preparing optically active lycorane and as a precursor for ligands in PET imaging highlights its advanced synthetic capabilities.

For procurement professionals tasked with sourcing chemical raw materials, identifying a dependable supplier of Dimethyl 1,3-acetonedicarboxylate is a strategic imperative. China-based manufacturers often provide a competitive edge, offering high-quality products at attractive price points, coupled with significant production capacity. When selecting a supplier, it is advisable to look for those who can provide certifications like GMP and SGS, ensuring that the intermediate meets international pharmaceutical standards. Furthermore, ease of access to product information, quote requests, and responsive customer support are key indicators of a reliable partner.

We are dedicated to supporting the pharmaceutical R&D community by providing high-purity Dimethyl 1,3-acetonedicarboxylate. As a trusted manufacturer, we understand the critical need for quality and consistency. We encourage pharmaceutical companies to buy this essential intermediate from us, knowing that we are committed to offering competitive pricing and ensuring a stable supply. Reach out to us today to discuss your requirements and secure your source for this vital pharmaceutical building block.