In the intricate world of Active Pharmaceutical Ingredient (API) synthesis, the selection of high-quality intermediates is critical for success. Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate, identified by CAS number 96568-04-6, is a prime example of such a vital component. This pyridine derivative, characterized by its specific halogen substitutions and acetoacetate functional group, offers unique reactivity that makes it indispensable in several pharmaceutical manufacturing processes. As a supplier of this essential compound, we aim to provide clarity on its properties and applications for our B2B clientele.

The chemical structure of Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate confers upon it a distinct profile of physical and chemical properties. Typically appearing as an off-white powder, its melting point generally falls between 68-72°C. These characteristics are important for formulators and process chemists to consider during handling and reaction optimization. The presence of chlorine and fluorine atoms significantly influences its reactivity, making it a versatile building block in multi-step syntheses.

The primary utility of this chemical lies in its role as an intermediate for sophisticated drug molecules. Most notably, it is a precursor in the synthesis of Gemifloxacin mesylate, a broad-spectrum fluoroquinolone antibiotic known for its efficacy. For pharmaceutical companies looking to manufacture such essential medicines, securing a reliable supply of this intermediate is paramount. When seeking to purchase this compound, it's advisable to engage with established chemical manufacturers who can guarantee purity and consistency. Exploring pricing from reputable suppliers in China can also offer a competitive advantage.

Understanding the specifications, such as purity levels (typically ≥98.5%) and acceptable impurity limits (≤0.6%), is crucial when procuring Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate. These parameters directly impact the yield and quality of the final API. Engaging with a knowledgeable manufacturer that can provide detailed technical data and support is beneficial for R&D scientists and procurement specialists alike. This ensures that your supply chain for this key intermediate remains robust and efficient.