The pharmaceutical industry relies heavily on a robust supply of fine chemicals, which serve as the fundamental building blocks for Active Pharmaceutical Ingredients (APIs). These complex molecules, often produced through intricate multi-step synthesis, demand exceptional purity and precise chemical structures to ensure the efficacy and safety of the final drug product. In this context, understanding the role and sourcing of specific intermediates like (alphaS,3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-alpha-(phenylmethyl)-1-piperidinepropanoic acid (CAS 156130-41-5) is vital for any research scientist or procurement manager in the pharmaceutical sector.

What are Fine Chemicals and Pharmaceutical Intermediates?

Fine chemicals are typically single, pure chemical substances, produced in limited quantities using advanced synthesis processes. Pharmaceutical intermediates, a subset of fine chemicals, are compounds that are synthesized during the production of an API. They are not the final drug product but are crucial precursors. The quality of an intermediate directly impacts the quality of the final API. Therefore, sourcing from reputable manufacturers is essential. A reliable supplier, often found in regions like China known for its chemical manufacturing prowess, can provide intermediates such as CAS 156130-41-5 with the required specifications, typically ≥99% purity and in a consistent white powder form.

The Significance of (alphaS,3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-alpha-(phenylmethyl)-1-piperidinepropanoic Acid

The chemical (alphaS,3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-alpha-(phenylmethyl)-1-piperidinepropanoic acid, identified by CAS number 156130-41-5, is a prime example of a specialized pharmaceutical intermediate. With its molecular formula C23H29NO3 and molecular weight of 367, it possesses a complex chiral structure, making its synthesis demanding. Its application as a precursor in the development of new drug molecules underscores the importance of its precise stereochemistry and high purity. Companies seeking to buy this compound for their research and development efforts or for pilot-scale production look for manufacturers who can guarantee consistent quality and provide comprehensive documentation.

Sourcing Strategies for Pharmaceutical Intermediates

When sourcing intermediates like CAS 156130-41-5, several strategies are employed by R&D teams and procurement departments. Firstly, identifying manufacturers in China that offer competitive pricing and possess strong manufacturing capabilities is a common approach. These manufacturers often provide a wide range of transportation options, including air and sea freight, and adhere to international trade standards (Incoterms). Secondly, focusing on suppliers who can provide technical support, custom synthesis options, and timely delivery is crucial. Whether you require a quote for a specific quantity or need to ensure consistent supply for ongoing projects, a transparent and efficient supplier relationship is key.

The development of novel therapeutics is an intricate process, and the role of high-quality fine chemicals and pharmaceutical intermediates cannot be overstated. By understanding the specific requirements and engaging with reliable manufacturers, the pharmaceutical industry can continue to innovate and bring life-changing medicines to market.