Bioconjugation and molecular imaging are rapidly advancing fields, constantly seeking novel reagents that offer greater precision and versatility. Iodine-substituted amino acids, such as Fmoc-4-iodo-L-phenylalanine (CAS 82565-68-2), are proving to be indispensable tools in these areas. Their unique chemical properties, particularly the presence of the iodine atom, enable sophisticated modifications crucial for both diagnostic and therapeutic applications. As a dedicated supplier of high-quality biochemicals, NINGBO INNO PHARMCHEM CO.,LTD. provides essential materials for such cutting-edge research.

Fmoc-4-iodo-L-phenylalanine is a synthetically modified amino acid that combines the benefits of Fmoc protection for peptide synthesis with the reactive potential of an iodine atom on its side chain. The Fmoc group ensures compatibility with standard peptide synthesis protocols, allowing for the controlled incorporation of this specialized residue into peptide sequences. For researchers looking to buy these advanced reagents, understanding the synergy between the protecting group and the functional substitution is key.

The iodine atom itself is the core element driving its utility in bioconjugation and imaging. Iodine is a relatively heavy atom that can be isotopically labeled, most notably with radioisotopes like Iodine-123 or Iodine-125. These radiolabeled peptides can then be used as tracers in positron emission tomography (PET) or single-photon emission computed tomography (SPECT) imaging, allowing for the visualization and quantification of biological processes or the tracking of drug delivery in vivo. The carbon-iodine bond is also susceptible to various radiolabeling reactions, making Fmoc-4-iodo-L-phenylalanine an excellent precursor for radiopharmaceutical development.

Beyond radiolabeling, the iodine atom facilitates facile chemical modification through cross-coupling reactions. This allows researchers to attach fluorescent probes, affinity tags, or therapeutic payloads to the peptide backbone at a specific position. Such modifications are vital for developing targeted therapies, diagnostic assays, and sophisticated biochemical tools. NINGBO INNO PHARMCHEM CO.,LTD. is a reliable manufacturer and supplier of high-purity Fmoc-4-iodo-L-phenylalanine, supporting the critical work of scientists in these fields. If you are exploring opportunities in bioconjugation or molecular imaging, we encourage you to inquire about our product and explore how our intermediates can advance your research objectives.