The study of enzymes and their catalytic roles is fundamental to advancements in biochemistry and pharmacology. Dihydroorotate dehydrogenase (DHODH) is one such enzyme, playing a critical part in the de novo pyrimidine biosynthetic pathway. Its substrate, L-Dihydroorotic Acid (CAS 5988-19-2), is therefore a compound of immense interest to researchers worldwide. Understanding the interaction between L-Dihydroorotic Acid and DHODH is key to unlocking insights into cellular metabolism and developing targeted therapies.

L-Dihydroorotic Acid, a chemical characterized by its white to off-white crystalline powder appearance, is integral to the synthesis of pyrimidine nucleotides, essential components of nucleic acids. The enzyme DHODH catalyzes the oxidation of L-Dihydroorotic Acid to orotic acid. This reaction is not only a rate-limiting step but also represents a potential target for drug development, particularly in areas like cancer and autoimmune diseases where pyrimidine synthesis is often dysregulated.

For researchers aiming to buy L-Dihydroorotic Acid, ensuring high purity is crucial for accurate enzyme kinetic studies and effective inhibitor screening. A reliable manufacturer will supply L-Dihydroorotic Acid with a guaranteed purity of 98% or higher, providing the consistency needed for reproducible results. As a supplier, we understand the stringent requirements of DHODH research and are dedicated to providing a dependable source of this vital compound.

The significance of L-Dihydroorotic Acid extends beyond its direct substrate role. It can also serve as a potential biomarker for assessing pyrimidine synthesis activity, aiding in the clinical development of DHODH inhibitors. By studying the concentration or turnover of L-Dihydroorotic Acid, researchers can gain valuable information about the metabolic state of cells or tissues.

When you choose to purchase L-Dihydroorotic Acid, partnering with a manufacturer that prioritizes quality and offers strong technical support is essential. Whether you are conducting fundamental enzyme kinetics or exploring novel therapeutic targets, a consistent supply of pure L-Dihydroorotic Acid from a reputable supplier in China will significantly contribute to the success of your research projects.