The pharmaceutical industry relies on a complex web of specialized chemical intermediates to bring life-saving and life-improving drugs to market. Among these, Methyl 3-(3-(trifluoromethyl)phenyl)acrylate (CAS: 87087-35-2) stands out for its indispensable role in the synthesis of Cinacalcet and Cinacalcet hydrochloride. These medications are vital for patients managing conditions like secondary hyperparathyroidism, making the consistent supply of high-quality intermediates a critical concern for manufacturers worldwide.

Methyl 3-(3-(trifluoromethyl)phenyl)acrylate is a precisely engineered molecule, characterized by its trifluoromethyl group and an acrylate ester. This structural configuration makes it an ideal precursor in the multi-step synthesis of Cinacalcet. The trifluoromethyl group, in particular, often imparts increased lipophilicity and metabolic stability to the final drug molecule, properties that are highly desirable in pharmaceutical design. Its molecular formula, C11H9F3O2, and molecular weight of approximately 230.18 g/mol, are fundamental to its reactivity and application.

As a key Cinacalcet intermediate, its availability from reliable manufacturers is essential. For R&D scientists and product development teams, sourcing this compound with guaranteed purity (typically ≥97%) is non-negotiable. The chemical and physical properties, such as its appearance as a white powder, density of ~1.3 g/cm³, and a flash point around 98.7°C, also dictate its handling and processing requirements.

Companies looking to purchase Methyl 3-(3-(trifluoromethyl)phenyl)acrylate often seek a reliable supplier who can provide both quality and volume. The global market for this intermediate is supported by specialized chemical manufacturers, with China being a significant hub for production. When you are looking to buy this critical component, engaging with manufacturers who understand the stringent demands of the pharmaceutical sector is paramount. They should be able to provide comprehensive documentation, including Certificates of Analysis (CoA), to confirm product specifications.

The economic aspect is also crucial. Understanding the price of Methyl 3-(3-(trifluoromethyl)phenyl)acrylate, especially for bulk quantities, is a key part of procurement strategy. Manufacturers in regions with established chemical industries, like China, can often offer competitive pricing due to economies of scale and optimized production processes. This makes them an attractive option for pharmaceutical companies aiming to manage production costs effectively.

In summary, Methyl 3-(3-(trifluoromethyl)phenyl)acrylate is far more than just another chemical compound; it is a vital link in the chain of producing important medications. Its role as a pharmaceutical intermediate for Cinacalcet highlights the intricate and essential nature of the specialty chemical industry. Sourcing this compound from reputable manufacturers ensures that the development and availability of these crucial drugs continue uninterrupted.