In the dynamic field of organic synthesis, certain molecules emerge as indispensable tools for chemists. 3-Iodophenol (CAS 626-02-8) is one such compound, valued for its dual functionality and versatility. This article delves into the critical roles 3-Iodophenol plays in contemporary organic chemistry, highlighting its utility as a chemical intermediate and reagent. For R&D scientists and formulation chemists, understanding its reaction capabilities is key to designing efficient synthetic routes and developing innovative products. We aim to provide insight into why sourcing this compound from a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. is advantageous.

The structural features of 3-Iodophenol, specifically the presence of a hydroxyl group and an iodine atom on a benzene ring, confer a rich reactivity profile. The phenolic hydroxyl group allows for typical reactions of phenols, such as etherification and esterification, enabling the introduction of various functional groups. Simultaneously, the iodine atom is an excellent leaving group, making the molecule a prime substrate for a wide array of metal-catalyzed cross-coupling reactions. These reactions are foundational in modern synthetic strategies, allowing for the efficient formation of carbon-carbon and carbon-heteroatom bonds, which are essential for building complex organic structures.

One of the most significant applications of 3-Iodophenol lies in its participation in transition metal-catalyzed cross-coupling reactions. For instance, in Suzuki-Miyaura coupling, the aryl iodide readily reacts with organoboron compounds in the presence of a palladium catalyst to form new carbon-carbon bonds. Similarly, Heck reactions allow for the vinylation of the aromatic ring, and Sonogashira couplings enable the introduction of alkynyl groups. These methodologies are frequently employed in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. If your research involves these powerful synthetic tools, consider exploring our offerings for high-quality 3-Iodophenol.

Beyond its role in coupling reactions, 3-Iodophenol is also employed in other important transformations such as nucleophilic aromatic substitution under specific conditions, and in the preparation of various chemical probes used in biological imaging and molecular sensing. Its utility in crafting cell-permeable probes underscores its importance in life science research. For those seeking to buy 3-Iodophenol for these specialized applications, understanding the purity and supply stability is critical.

As a leading chemical manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing researchers and manufacturers with access to high-quality 3-Iodophenol. We understand that the success of your research and production depends on the reliability of your raw materials. We offer competitive pricing for this essential intermediate and are equipped to handle orders from laboratory scale to bulk quantities. Contact us today to learn more about our product specifications, availability, and to obtain a quote.