For researchers and product formulators engaged in cutting-edge organic synthesis, understanding the nuances of key intermediates is vital. 3-Nitropyridine-2,4-diol, commonly known by its CAS number 89282-12-2 and often referred to as 2,4-Dihydroxy-3-nitropyridine, is one such compound. Its unique chemical structure makes it a highly sought-after building block for creating complex molecules with diverse functionalities. This article highlights its significance and potential applications in modern chemical research and development.

Chemical Profile and Reactivity

The compound C5H4N2O4, weighing approximately 156.10 g/mol, features a pyridine core substituted with two hydroxyl groups and a nitro group. The electron-withdrawing nature of the nitro group and the nucleophilic potential of the hydroxyl groups contribute to its varied reactivity. This dual nature allows it to participate in a range of chemical transformations, making it an attractive intermediate for synthetic chemists. Its typical appearance as a white to pale yellow powder underscores the need for precise handling and storage to maintain its integrity.

Applications in Synthesis

3-Nitropyridine-2,4-diol serves as a crucial starting material or intermediate in the synthesis of a wide array of heterocyclic compounds. Its utility is particularly pronounced in the pharmaceutical industry, where it can be elaborated into more complex structures with potential biological activity. R&D scientists often utilize it for:

  • Heterocyclic Synthesis: Building advanced pyridine-based scaffolds.
  • Functional Group Modifications: The hydroxyl and nitro groups can be further reacted to introduce diverse functionalities.
  • Pharmaceutical Intermediates: As a precursor for APIs, its precise chemical structure is key.

When considering purchasing this chemical, looking for suppliers that can guarantee high purity 3-nitropyridine-2,4-diol is essential. Working with a dedicated chemical manufacturer ensures that you receive materials that meet stringent quality standards, vital for reproducible and successful synthetic outcomes. Exploring the price of this compound from reliable sources will also be a key factor in your research budget.

NINGBO INNO PHARMCHEM CO., LTD. offers a reliable source for 2,4-Dihydroxy-3-nitropyridine, supporting your research and development efforts with high-quality materials. We understand the demands of advanced organic synthesis and are committed to being your trusted partner.