The pharmaceutical industry constantly seeks high-quality raw materials and intermediates to develop life-saving and diagnostic drugs. Among these, certain organic compounds play pivotal roles as building blocks. 3,5-Dinitro-2-methylbenzoic acid (CAS 28169-46-2) stands out as a critical intermediate, particularly in the synthesis of advanced pharmaceutical products like X-ray contrast agents. Understanding its properties and the importance of reliable sourcing is key for R&D scientists and procurement professionals.

Chemical Properties and Significance

3,5-Dinitro-2-methylbenzoic acid is an aromatic organic compound characterized by a benzoic acid core with two nitro groups and a methyl group attached. Its molecular formula is C8H6N2O6, and it typically presents as an off-white to pale yellow crystalline powder. The compound’s specific arrangement of functional groups makes it highly reactive and suitable for various organic synthesis pathways. Purity is a critical factor, with an assay of ≥99% being common and often required for pharmaceutical applications. When you buy this chemical, its consistent quality and stability are essential for predictable reaction outcomes.

Critical Use in X-ray Contrast Agent Synthesis

One of the most significant applications of 3,5-Dinitro-2-methylbenzoic acid is its use as a precursor in the synthesis of X-ray contrast agents. A prime example is Diatrizoic Acid, a well-established agent used in medical imaging procedures such as CT scans and angiography. These contrast agents enhance the visibility of internal organs and tissues by altering the absorption of X-rays, thereby improving diagnostic accuracy. The high purity of the 3,5-Dinitro-2-methylbenzoic acid used in these syntheses directly impacts the quality and safety of the final pharmaceutical product. Therefore, purchasing this intermediate from a reputable manufacturer that guarantees strict quality control is imperative.

Beyond Contrast Agents: Other Pharmaceutical Roles

While its role in contrast agents is prominent, 3,5-Dinitro-2-methylbenzoic acid may also be involved in the synthesis of other therapeutic molecules or as a reagent in specific organic transformations within pharmaceutical research and development. Its utility as a chemical building block means it can be adapted for various novel drug discovery programs. The ability to buy this compound from reliable suppliers ensures that pharmaceutical companies can continue their research and manufacturing without interruption.

Procurement Considerations for R&D and Production

For those seeking to purchase 3,5-Dinitro-2-methylbenzoic acid, several factors are critical:

  • Purity and Assay: Ensure the product meets the required ≥99% assay, as specified by your R&D protocols or manufacturing standards.
  • Supplier Reputation: Opt for manufacturers or suppliers with a strong track record in delivering high-quality pharmaceutical intermediates. A trusted supplier, especially one from China, can offer both quality and competitive pricing.
  • Regulatory Compliance: Confirm that the product complies with relevant industry standards (e.g., USP, BP, EP) if it's intended for pharmaceutical use.
  • Technical Support: A supplier that provides comprehensive technical documentation and responsive customer service can greatly facilitate the procurement process.

By carefully considering these aspects, pharmaceutical professionals can secure a dependable supply of 3,5-Dinitro-2-methylbenzoic acid, thereby supporting the continuous innovation and production within the healthcare sector.

(This content is intended for informational purposes only. Always consult product specifications and supplier documentation for accurate details.)