In the intricate world of pharmaceutical research and development, the availability of high-quality intermediates is the bedrock upon which new therapies are built. 4-(4-Aminophenoxy)-N-methylpicolinamide, identified by its CAS number 284462-37-9, stands out as a pivotal compound, particularly within the realm of targeted therapies. This article delves into the significance of this intermediate and how its procurement from reliable manufacturers and suppliers is essential for advancing drug discovery pipelines.

The primary utility of 4-(4-Aminophenoxy)-N-methylpicolinamide lies in its function as a key intermediate for synthesizing a range of kinase inhibitors. Kinases are enzymes that play crucial roles in cell signaling pathways. Aberrant kinase activity is frequently associated with diseases such as cancer, making kinase inhibitors a vital class of therapeutics. The specific molecular structure of 4-(4-Aminophenoxy)-N-methylpicolinamide, featuring an aminophenoxy group linked to a methylpicolinamide moiety, provides a versatile scaffold that medicinal chemists can derivatize to create potent and selective inhibitors.

For researchers and product formulators, sourcing this intermediate demands an assurance of purity and consistency. A minimum purity of 98% is typically required, often verified through rigorous analytical testing. When you buy 4-(4-Aminophenoxy)-N-methylpicolinamide, you are investing in the success of your synthesis. Variations in purity or the presence of unwanted by-products can lead to failed reactions, extended development timelines, and increased costs. Therefore, engaging with manufacturers who adhere to strict quality control standards is paramount.

The global chemical supply chain offers numerous options for acquiring this compound. However, for large-scale projects or consistent R&D needs, identifying a stable manufacturer is critical. Companies specializing in fine chemicals and pharmaceutical intermediates, especially those based in manufacturing hubs like China, often provide competitive pricing and reliable supply. When seeking a supplier, consider their production capacity, regulatory compliance (e.g., ISO certifications), and ability to provide comprehensive technical documentation. Exploring options for custom synthesis can also be beneficial if specific structural modifications or quantities are needed.

The importance of 4-(4-Aminophenoxy)-N-methylpicolinamide cannot be overstated in the context of modern drug development. Its role in creating targeted therapies offers hope for more effective treatments with fewer side effects. As the demand for novel pharmaceuticals continues to grow, so does the need for a dependable supply of these crucial building blocks. By understanding the applications and diligently selecting your manufacturer or supplier, you can ensure your projects are well-equipped for success.