The landscape of drug discovery is constantly evolving, driven by the need for novel therapeutic agents. Central to this progress is the availability of specialized chemical intermediates that enable the synthesis of complex drug candidates. Among these, 5-Bromo-3-methylquinazolin-4(3H)-one (CAS: 1410973-83-9) stands out as a valuable heterocyclic building block, playing a pivotal role in the development of new medicines.

Understanding the Chemical Significance

As a quinazolinone derivative, 5-Bromo-3-methylquinazolin-4(3H)-one possesses a unique chemical structure that makes it highly adaptable for various synthetic pathways. Its molecular formula, C9H7BrN2O, and molecular weight of approximately 239.07 g/mol, are well-defined, facilitating predictable reaction outcomes. The presence of a bromine atom on the quinazolinone ring offers a convenient handle for further chemical modifications, such as cross-coupling reactions, which are fundamental in building complex molecular architectures required for drug efficacy.

Applications in Pharmaceutical R&D

This intermediate is extensively used in medicinal chemistry for the synthesis of compounds with a wide range of biological activities. It is frequently employed in the early stages of drug discovery, where researchers explore structure-activity relationships (SAR). By incorporating this building block into potential drug molecules, scientists can investigate its impact on target binding, metabolic stability, and pharmacokinetic properties. Its utility as a reliable intermediate allows for the efficient creation of compound libraries, accelerating the screening process for new drug leads.

Procurement for Research and Development

For research institutions and pharmaceutical companies, securing a dependable supply of high-quality 5-Bromo-3-methylquinazolin-4(3H)-one is essential. Many organizations look to established chemical manufacturers and suppliers, particularly those with a strong presence in markets like China, to fulfill their needs. When you need to buy this compound, focusing on suppliers that guarantee high purity (often 97%+) and provide comprehensive technical documentation ensures the integrity of your research.

Partnering with a Manufacturer for Your Needs

Working with a specialized manufacturer can offer significant advantages, including access to competitive pricing for bulk orders and customized synthesis services. By establishing a relationship with a trusted supplier, R&D teams can ensure a consistent flow of critical materials, facilitating uninterrupted progress in their projects. Whether for bench-scale experiments or larger pilot studies, having a reliable source is invaluable.

NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the pharmaceutical industry by providing essential intermediates. Our high-purity 5-Bromo-3-methylquinazolin-4(3H)-one is available for your drug discovery programs. Contact us for a quote and to discuss your specific requirements.