In the intricate world of pharmaceutical manufacturing, the quality and availability of chemical intermediates are foundational to the entire process. One such vital compound is 6-Cyclohexyl-4-methyl-2H-pyran-2-one, known by its CAS number 14818-35-0. This specific pyranone derivative serves as a key building block, most notably in the synthesis of Ciclopirox, a widely prescribed antifungal medication. For pharmaceutical professionals, understanding its role and securing a reliable supply is paramount.

Understanding 6-Cyclohexyl-4-methyl-2H-pyran-2-one

6-Cyclohexyl-4-methyl-2H-pyran-2-one is characterized by its molecular formula C12H16O2 and a molecular weight of approximately 192.25 g/mol. Its physical properties typically include a white powder appearance, with a purity assay often exceeding 98.0%. These characteristics make it a preferred choice for chemical synthesis where precise molecular structures and high purity are essential. Its primary application lies in its function as an intermediate in the production of Ciclopirox, an agent effective against a range of fungal infections.

The Synthesis Pathway and Sourcing Considerations

The synthesis of Ciclopirox relies heavily on the availability of high-quality 6-Cyclohexyl-4-methyl-2H-pyran-2-one. Pharmaceutical companies and contract manufacturing organizations (CMOs) must ensure a consistent supply chain for this critical raw material. When looking to buy 14818-35-0, it is important to consider suppliers who can provide:

  • Certified Purity: Ensuring the intermediate meets pharmacopeial standards or stringent in-house specifications is crucial. Suppliers offering a high assay (u226598.0%) are preferred.
  • Reliable Manufacturing: Partnering with a reputable pharmaceutical intermediate supplier ensures that production processes are robust and that the compound is consistently manufactured to meet demand.
  • Traceability and Documentation: Access to comprehensive technical data, Certificates of Analysis (CoA), and potentially pharmacopeial traceability is essential for regulatory compliance and quality assurance.
  • Competitive Pricing: Obtaining a favorable price for 6-cyclohexyl-4-methyl-2h-pyran-2-one without compromising on quality is a key objective for procurement managers.

The demand for effective antifungal treatments like Ciclopirox means that the supply of its precursor, 6-Cyclohexyl-4-methyl-2H-pyran-2-one, is a critical component of the global pharmaceutical supply chain. Researchers and manufacturers seeking this compound are encouraged to connect with experienced chemical suppliers who can offer both quality assurance and a dependable supply.