In the intricate world of pharmaceutical development, the quality and availability of key intermediates are paramount. 9-Oxo-10(9H)-Acridineacetic Acid (CAS 38609-97-1) stands out as a versatile and important molecule, serving as a foundational component in the synthesis of a range of potential therapeutic agents. This article delves into the significance of this compound as a pharmaceutical intermediate, exploring its properties, applications in drug discovery, and the importance of reliable sourcing from a dedicated manufacturer.

Understanding its Pharmaceutical Significance

9-Oxo-10(9H)-Acridineacetic Acid belongs to the acridine class of compounds, known for their rigid planar structure and biological activities. Its specific molecular architecture, featuring an acetic acid moiety attached to the acridone core, makes it an attractive starting material for medicinal chemists. Research has highlighted its potential as an interferon inducer, a property that is actively being investigated for its role in immunomodulatory therapies and as an adjunct in treating certain types of cancers, such as endometrial cancer, by potentially increasing sensitivity to progestin therapies.

As a building block, it allows for the introduction of the acridone scaffold into more complex molecular structures. This capability is vital for creating novel drug candidates that aim to interact with specific biological targets. The synthesis of these advanced pharmaceuticals often requires intermediates with high purity and consistent quality, emphasizing the need to buy 9-Oxo-10(9H)-Acridineacetic Acid from suppliers who can guarantee these attributes.

Sourcing and Quality Assurance

For pharmaceutical companies and research institutions, securing a consistent supply of high-quality 9-Oxo-10(9H)-Acridineacetic Acid is a critical operational requirement. When seeking to purchase this intermediate, it is essential to partner with a reputable supplier or manufacturer. Key quality indicators to look for include:

  • Purity: Typically specified as ≥99.0%, often validated by analytical techniques like HPLC or GC-MS.
  • CAS Number: Confirmation of CAS 38609-97-1 ensures the correct chemical is identified.
  • Regulatory Compliance: While the product itself may be for R&D purposes, working with suppliers who understand and adhere to general chemical industry quality standards is crucial.
  • Technical Documentation: Availability of a comprehensive Certificate of Analysis (COA), Safety Data Sheet (SDS), and technical specifications from the manufacturer builds confidence in the product's suitability for downstream processes.

Engaging with Manufacturers for Bulk Orders

When large-scale synthesis is required, engaging directly with a manufacturer, particularly one based in China, can offer significant cost advantages and supply volume. Requesting a detailed quote that outlines pricing per kilogram or metric ton, lead times, and packaging options is a standard practice. It is also advisable to inquire about their production capacity and their ability to meet stringent quality control measures required for pharmaceutical applications.

Conclusion

9-Oxo-10(9H)-Acridineacetic Acid plays a pivotal role as a pharmaceutical intermediate, offering unique properties for drug discovery and development. Its potential as an interferon inducer and its utility as a chemical scaffold make it a valuable asset. By prioritizing purity, reliability, and direct engagement with manufacturers, pharmaceutical companies can ensure they obtain the high-quality materials necessary for advancing their research and manufacturing pipelines.