Histology, the study of the microscopic anatomy of cells and tissues, relies heavily on stains to visualize cellular structures and differentiate between various components. Among the classic stains, Neutral Red, also known by its synonym Basic Red 5 and identified by CAS 553-24-2, holds a significant place. As a premier chemical supplier, we provide researchers and histologists with high-quality Neutral Red, ensuring the precision and clarity required for detailed tissue analysis. Understanding its application in histology can help laboratories worldwide to buy this essential dye with confidence.

Neutral Red is a diamino-phenazine dye that functions as a metachromatic stain, meaning it can stain different tissues or cellular components in varying colors. However, its most prominent characteristic is its affinity for acidic mucins and the lysosomes within cells. When used in histological preparations, Neutral Red stains the cytoplasm and lysosomes a distinct red or pinkish-red color, while the nucleus typically remains unstained or takes on a paler hue, depending on counterstaining. This differential staining allows for clear visualization of cell morphology and intracellular structures, making it a valuable tool in diagnostic pathology and fundamental biological research.

The mechanism behind Neutral Red's effectiveness in histology lies in its electrostatic interactions and its ability to accumulate in specific cellular compartments. As a basic dye, it readily binds to anionic sites within the cell, particularly in the acidic environment of lysosomes. This selective uptake and retention are key to its utility. Many histology protocols incorporate Neutral Red to highlight specific cellular features or to assess cellular health by observing lysosomal integrity. When professionals seek to buy Basic Red 5, they are often looking for a dye that provides consistent and predictable staining patterns, which is precisely what we aim to deliver as a dedicated chemical manufacturer.

For laboratories that require a steady supply of this vital stain, purchasing from a reputable chemical supplier is essential. The quality and purity of the dye directly impact the success of staining procedures. Impurities can lead to inconsistent staining, background artifacts, or reduced intensity. Therefore, making an informed decision when you need to buy Neutral Red for your histology lab is critical. Our commitment as a manufacturer is to ensure that every batch of Basic Red 5 meets stringent quality controls, providing you with a reliable reagent for all your histological staining needs. Whether you are performing routine tissue preparation or advanced research, our high-grade Neutral Red is available to support your work.