Acalabrutinib has emerged as a significant therapeutic agent in the treatment of certain hematological malignancies. Its efficacy is intrinsically linked to the precise chemical structure of its precursors, among which Benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate plays a pivotal role. This article explores the significance of this intermediate for pharmaceutical manufacturers and researchers seeking to purchase high-quality materials.

Understanding the Intermediate's Function

Benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate, identified by CAS No. 1420478-88-1, is a complex heterocyclic compound. Its intricate structure contains several key functional groups and a specific chiral center, which are essential for its subsequent transformation into Acalabrutinib through a series of carefully controlled chemical reactions. The synthesis of Acalabrutinib involves coupling this intermediate with other molecular fragments, highlighting the importance of its purity and structural integrity.

Sourcing Strategies for Pharmaceutical Companies

Pharmaceutical procurement professionals are constantly on the lookout for reliable suppliers who can deliver intermediates like Benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate with consistent quality and a stable supply chain. When searching for this compound, common queries include 'buy Benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate' or 'Acalabrutinib intermediate manufacturer China'. NINGBO INNO PHARMCHEM CO.,LTD. is a recognized supplier specializing in high-purity pharmaceutical intermediates. We ensure that our products meet rigorous specifications, such as a purity level of ≥99.0%, and are produced under controlled manufacturing conditions.

Key Properties and Applications

  • Chemical Identity: Benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate
  • CAS Number: 1420478-88-1
  • Molecular Formula: C18H18BrN5O2
  • Molecular Weight: 416.27
  • Appearance: Typically a white powder.
  • Primary Application: A key intermediate in the synthesis of Acalabrutinib.

The demand for high-quality Benzyl 2-(8-amino-1-bromoimidazo[1,5-a]pyrazin-3-yl)pyrrolidine-1-carboxylate is directly driven by the growing market for Acalabrutinib. Pharmaceutical companies looking to secure their supply chain should partner with experienced chemical manufacturers. By choosing a reputable supplier, such as NINGBO INNO PHARMCHEM CO.,LTD., you ensure the quality, reliability, and cost-effectiveness necessary for successful drug development and manufacturing. Contact us for a quote and to explore how we can support your pharmaceutical intermediate needs.