The pharmaceutical industry operates under some of the most stringent quality regulations globally. For manufacturers of cholesterol-lowering drugs like Rosuvastatin, sourcing high-quality raw materials and intermediates is a non-negotiable aspect of production. The intermediate tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate, identified by CAS 289042-12-2, plays a pivotal role in the synthesis pathway of Rosuvastatin Calcium.

This particular intermediate is characterized by its specific chemical structure, molecular formula C29H40FN3O6S, and a molecular weight of 577.71. Its physical form as a white to off-white powder is a standard attribute, but its purity is the defining characteristic that procurement managers and R&D scientists scrutinize. A high purity level, typically exceeding 99.0% as confirmed by HPLC, is essential. This high purity ensures that downstream reactions proceed efficiently, minimizing the formation of unwanted by-products and simplifying the purification process for the final Rosuvastatin API.

When seeking to buy this vital intermediate, understanding the supplier's capabilities is as important as understanding the product specifications. A reliable manufacturer from China will not only offer competitive pricing but also guarantee a consistent supply chain. This reliability is crucial for maintaining uninterrupted production schedules. Furthermore, transparency regarding impurity profiles—specifically, the single impurity content being less than 0.3% and total impurities less than 0.5%—is a hallmark of a reputable supplier.

The role of CAS 289042-12-2 extends beyond just being a chemical precursor; it is a critical control point in the overall quality assurance of Rosuvastatin manufacturing. Pharmaceutical companies must ensure that their suppliers adhere to strict quality management systems, providing comprehensive documentation such as Certificates of Analysis (CoA). For those involved in API production, partnering with a manufacturer that understands the pharmaceutical industry's demands for purity, consistency, and regulatory compliance is paramount.

For businesses in the pharmaceutical sector looking for a trustworthy source of Rosuvastatin intermediate R1, exploring options from established Chinese chemical manufacturers is a strategic move. By prioritizing suppliers who offer detailed specifications, reliable delivery, and competitive pricing, companies can secure the foundational components necessary for producing high-quality Rosuvastatin APIs. Engaging with NINGBO INNO PHARMCHEM CO.,LTD. can provide access to these essential pharmaceutical intermediates.