The Role of Chiral Intermediates in Ezetimibe Synthesis
The synthesis of Active Pharmaceutical Ingredients (APIs) often relies on complex chiral intermediates. These molecules, possessing specific three-dimensional structures, are fundamental to the efficacy and safety of many modern drugs. One such critical intermediate is (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyl-2-oxazolidinone, identified by its CAS number 189028-93-1.
This compound plays a pivotal role in the synthesis of ezetimibe, a widely prescribed medication renowned for its ability to lower cholesterol levels by inhibiting intestinal cholesterol absorption. The specific stereochemistry of the (4S) configuration is not merely an academic detail; it is paramount for the drug's targeted action and pharmacological effectiveness. Deviations in stereochemistry can lead to reduced efficacy or even unwanted side effects.
As a specialized pharmaceutical intermediate manufacturer, understanding and delivering this precise chirality is our core competency. We ensure that our production processes for (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyl-2-oxazolidinone are meticulously controlled to guarantee the required purity and stereochemical integrity. This focus on quality is what makes us a trusted supplier for pharmaceutical companies worldwide.
For companies looking to buy this essential intermediate, sourcing from a reputable manufacturer is crucial. The competitive landscape of API manufacturing demands not only cost-effectiveness but also unwavering reliability in supply and quality. When you inquire about the price of (4S)-3-[5-(4-Fluorophenyl)-1,5-dioxopentyl]-4-phenyl-2-oxazolidinone, you are investing in the foundation of a life-saving medication. Our facility in China is equipped to handle large-scale production, ensuring that we can meet the demands of both research and commercial manufacturing. We are committed to being your go-to supplier for high-quality pharmaceutical intermediates.
 
                
Perspectives & Insights
Bio Analyst 88
“This compound plays a pivotal role in the synthesis of ezetimibe, a widely prescribed medication renowned for its ability to lower cholesterol levels by inhibiting intestinal cholesterol absorption.”
Nano Seeker Pro
“The specific stereochemistry of the (4S) configuration is not merely an academic detail; it is paramount for the drug's targeted action and pharmacological effectiveness.”
Data Reader 7
“Deviations in stereochemistry can lead to reduced efficacy or even unwanted side effects.”