The Role of CK-636 in Actin Dynamics and Cellular Migration
The actin cytoskeleton is a dynamic network of proteins essential for a myriad of cellular functions, including maintaining cell shape, enabling cell movement, and facilitating intracellular transport. The Arp2/3 complex is a key initiator of branched actin filament networks, crucial for processes like lamellipodia extension and filopodia formation, which are fundamental to cell migration. As a leading manufacturer of specialized biochemicals, we offer CK-636, a potent inhibitor that precisely targets this complex.
CK-636 (CAS 442632-72-6) is renowned for its ability to inhibit actin polymerization induced by the Arp2/3 complex. For researchers and product formulators, understanding the impact of this inhibition is vital. Studies have shown that compounds like CK-636 can reduce lamellipodia formation at the leading edges of migrating cells, thereby decreasing their velocity. This makes CK-636 an indispensable tool for scientists investigating cell motility, cytoskeletal remodeling, and the mechanics of cellular movement.
As a dedicated supplier, we provide high-purity CK-636 to support cutting-edge research. Purchasing CK-636 from our facility in China ensures access to a reliable source for your experimental needs. Our product is ideal for in vitro studies and as a pharmaceutical intermediate in early-stage drug development, particularly for conditions involving aberrant cell migration or cytoskeletal dysfunction.
We encourage R&D scientists to consider CK-636 for their studies on actin dynamics. Its well-defined mechanism of action and high specificity make it a valuable asset. When you buy CK-636 from us, you benefit from our commitment to quality and our efficient supply chain, ensuring you can procure this essential research chemical with ease. For bulk orders or inquiries regarding pricing, please do not hesitate to contact our sales team.
Perspectives & Insights
Future Origin 2025
“CK-636 (CAS 442632-72-6) is renowned for its ability to inhibit actin polymerization induced by the Arp2/3 complex.”
Core Analyst 01
“For researchers and product formulators, understanding the impact of this inhibition is vital.”
Silicon Seeker One
“Studies have shown that compounds like CK-636 can reduce lamellipodia formation at the leading edges of migrating cells, thereby decreasing their velocity.”