The Role of Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate in Modern Pharma
The pharmaceutical industry thrives on precision and purity. The synthesis of complex Active Pharmaceutical Ingredients (APIs) often relies on a series of carefully manufactured intermediates. Among these, Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate, identified by CAS number 147118-39-6, plays a pivotal role, particularly in the production of Rosuvastatin.
Rosuvastatin, a highly effective statin, is a cornerstone in managing hypercholesterolemia and reducing cardiovascular risks. Its intricate molecular structure is built step-by-step, with intermediates like CAS 147118-39-6 serving as essential building blocks. The specific (3R) stereochemistry of this compound is crucial for the enantiomeric purity of the final Rosuvastatin API, directly impacting its therapeutic efficacy and safety profile.
As a fine chemical, Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate is characterized by its molecular formula C23H28FN3O6S and a molecular weight of 493.55. Typically appearing as a white powder, its consistent quality is paramount for pharmaceutical manufacturers. Sourcing this intermediate requires a deep understanding of its chemical properties and the assurance of purity from the supplier.
For R&D scientists and procurement managers, the question is not just where to find this intermediate, but how to ensure its quality and reliability. Partnering with experienced manufacturers who specialize in pharmaceutical intermediates is key. Direct engagement with a manufacturer based in China, for example, can offer significant advantages. It allows for direct quality control, competitive pricing for bulk purchases, and a more predictable supply chain. When you buy this intermediate, you are investing in the integrity of your final drug product.
The implications of using a sub-standard intermediate can be severe, leading to failed batches, regulatory issues, and damage to a company's reputation. Therefore, choosing a manufacturer that adheres to stringent quality standards and can provide comprehensive documentation is essential. Our company, as a dedicated manufacturer of pharmaceutical intermediates, focuses on delivering Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate with guaranteed purity and consistent quality, making us a reliable partner for pharmaceutical synthesis needs.
In summary, Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate (CAS 147118-39-6) is more than just a chemical compound; it is a critical enabler of modern cardiovascular therapies. By understanding its importance and sourcing it from reputable manufacturers, the pharmaceutical industry can continue to deliver life-saving medications efficiently and safely. We invite you to request a quote and experience the reliability and quality we offer for your pharmaceutical intermediate requirements.
Perspectives & Insights
Molecule Vision 7
“The implications of using a sub-standard intermediate can be severe, leading to failed batches, regulatory issues, and damage to a company's reputation.”
Alpha Origin 24
“Therefore, choosing a manufacturer that adheres to stringent quality standards and can provide comprehensive documentation is essential.”
Future Analyst X
“In summary, Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate (CAS 147118-39-6) is more than just a chemical compound; it is a critical enabler of modern cardiovascular therapies.”