In the intricate world of pharmaceutical manufacturing, the quality and availability of key intermediates are paramount. One such compound, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine (CAS: 132335-44-5), plays a critical role, particularly in the synthesis of Duloxetine hydrochloride. As a leading pharmaceutical intermediate supplier in China, understanding the significance of this molecule is central to our mission.

Duloxetine hydrochloride is a widely prescribed medication used to treat conditions like major depressive disorder, generalized anxiety disorder, fibromyalgia, and neuropathic pain. The efficacy and safety of the final drug product are heavily dependent on the quality of its precursor intermediates. (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine, with its specific chiral configuration, is indispensable for producing the pharmacologically active enantiomer of Duloxetine. This underscores the importance of sourcing this intermediate from reputable manufacturers who can guarantee high purity and enantiomeric excess.

The chemical profile of (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine includes a molecular formula of C9H15NOS and a molecular weight of approximately 185.29 g/mol. Typically presented as an off-white to white powder, its key specifications often include a purity of ≥98.0%, a water content of ≤0.5%, and stringent limits on ash and heavy metals. These attributes are crucial for its successful integration into complex multi-step API synthesis pathways. Pharmaceutical companies worldwide actively seek reliable suppliers of this intermediate to ensure consistent production output and adherence to regulatory standards.

For businesses looking to buy this essential pharmaceutical building block, partnering with a trusted manufacturer in China offers distinct advantages. These include competitive pricing, scalability from kilograms to metric tons, and a robust understanding of global supply chain logistics. When evaluating potential suppliers, it is vital to inquire about their quality control processes, manufacturing capabilities, and their ability to provide comprehensive documentation, such as Certificates of Analysis (CoA) detailing purity and other critical parameters. This due diligence ensures that the sourced intermediate meets the exact requirements for your API production, mitigating risks and optimizing your manufacturing efficiency.

In conclusion, (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)propanamine is more than just a chemical compound; it is a gateway to essential pharmaceuticals that improve patient lives. As a dedicated provider, we are committed to delivering this high-quality intermediate, supporting the global pharmaceutical industry’s needs with reliability and excellence.