In the intricate world of pharmaceutical manufacturing, intermediate chemicals serve as the foundational blocks upon which life-saving medications are built. Tert-Butyl 4-aminophenethylcarbamate, identified by its CAS number 94838-59-2, stands out as a critical intermediate, particularly in the synthesis of the drug Mirabegron. This article delves into the properties, applications, and the importance of sourcing this compound from reputable manufacturers and suppliers.

The chemical structure of tert-Butyl 4-aminophenethylcarbamate features a benzene ring substituted with an ethylamine group, where the amine is protected by a tert-butyloxycarbonyl (Boc) group. This specific structure makes it an ideal precursor for incorporating a functionalized phenethylamine moiety into larger molecules. Its common synonyms include tert-butyl N-[2-(4-aminophenyl)ethyl]carbamate and 4-[2-(Boc-amino)ethyl]aniline, highlighting its key chemical features.

The primary application of tert-Butyl 4-aminophenethylcarbamate is its use as an intermediate in the synthesis of Mirabegron. Mirabegron is a selective $\beta_3$-adrenergic receptor agonist used to treat symptoms of overactive bladder (OAB), such as urinary urgency, frequency, and urge incontinence. The precise and high-purity nature of the starting materials is essential for efficient drug synthesis and to minimize the formation of unwanted by-products. As a manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. ensures that this intermediate meets the stringent quality requirements of the pharmaceutical industry.

When looking to purchase tert-Butyl 4-aminophenethylcarbamate, prospective buyers should pay close attention to its specifications. Typically, it is supplied as a white to off-white powder with an assay of ≥98.0%. This level of purity is critical for reliable reaction outcomes and regulatory compliance in pharmaceutical production. For researchers and developers, understanding where to buy from a dependable supplier in regions like China can offer significant advantages in terms of cost and accessibility.

The physical and chemical properties, such as a density of approximately 1.1 g/cm³ and a boiling point of around 396.8 °C, are indicative of its stability under standard laboratory and industrial conditions. These properties, coupled with its molecular formula (C₁₃H₂₀N₂O₂) and molecular weight (236.310 g/mol), are crucial data points for process chemists designing synthetic routes.

For businesses aiming to secure their supply chain for Mirabegron intermediates, partnering with a chemical company that can offer both quality assurance and competitive price is key. Companies often look for suppliers who can provide detailed technical documentation and support for their R&D and scale-up activities. Whether you need small quantities for research or bulk orders for commercial production, identifying the right manufacturer is a critical step.

In summary, tert-Butyl 4-aminophenethylcarbamate is more than just a chemical compound; it's a vital link in the chain of pharmaceutical innovation. Its role in Mirabegron synthesis underscores the importance of high-quality intermediates. For those seeking to buy this essential pharmaceutical intermediate, engaging with experienced suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to a reliable product with consistent quality and favorable pricing, facilitating the development and manufacturing of critical medicines.