The Role of tert-Butyl 6-cyano-2-intermediate in Targeted Cancer Therapies
The advancement of targeted cancer therapies has revolutionized oncology treatment, offering more precise and effective options for patients. Central to these therapies are complex molecules, and their efficient synthesis relies on high-quality pharmaceutical intermediates. Tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate, commonly known by its CAS number 1256584-75-4, stands out as a critical intermediate in this domain.
This specific indole derivative is a cornerstone in the manufacturing process of Alectinib. Alectinib is a potent and selective tyrosine kinase inhibitor designed to target anaplastic lymphoma kinase (ALK), a protein that, when mutated, can drive the growth of certain cancers, most notably non-small cell lung cancer (NSCLC). The precise chemical structure of tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate enables the subsequent complex chemical transformations required to build the Alectinib molecule.
For pharmaceutical R&D scientists and production managers, securing a reliable supply of this intermediate is vital. The typical specifications, such as an off-white to white powder appearance and a purity of ≥98.0%, are indicative of a well-manufactured chemical that can integrate seamlessly into complex synthetic routes. When sourcing, it is crucial to identify a chemical manufacturer or supplier that not only offers competitive pricing but also maintains stringent quality control measures and offers flexible packaging options to meet diverse project needs.
Many companies looking to buy this essential pharmaceutical intermediate opt for suppliers from China, leveraging the region's established expertise in fine chemical production. Engaging with these manufacturers for a price quote or to understand their supply capabilities is a common practice. As a dedicated supplier, we are committed to providing researchers and manufacturers with this high-purity intermediate, contributing to the development and accessibility of life-saving cancer treatments. Partner with us for your chemical intermediate needs.
Perspectives & Insights
Data Seeker X
“The precise chemical structure of tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate enables the subsequent complex chemical transformations required to build the Alectinib molecule.”
Chem Reader AI
“For pharmaceutical R&D scientists and production managers, securing a reliable supply of this intermediate is vital.”
Agile Vision 2025
“The typical specifications, such as an off-white to white powder appearance and a purity of ≥98.”