In the ongoing effort to combat cardiovascular diseases, Angiotensin-Converting Enzyme (ACE) inhibitors play a pivotal role. Trandolapril, identified by its CAS number 87679-37-6, is a prominent member of this class, offering distinct pharmacological advantages. This article explores the functional significance of Trandolapril in modern hypertension management and discusses the importance of sourcing this compound from reliable providers.

Mechanism of Action: How Trandolapril Works

Trandolapril functions as a prodrug, which is converted in the body to its active metabolite, trandolaprilat. Trandolaprilat is a potent inhibitor of the ACE enzyme. ACE is responsible for converting angiotensin I into angiotensin II, a peptide hormone that causes blood vessels to constrict, thereby raising blood pressure. By inhibiting ACE, Trandolapril effectively reduces the levels of angiotensin II, leading to vasodilation (widening of blood vessels) and a subsequent decrease in blood pressure. This makes Trandolapril a crucial therapeutic agent for individuals suffering from hypertension.

Pharmacological Advantages and Applications

Compared to other ACE inhibitors, Trandolapril is noted for its high lipophilicity and the prolonged duration of its inhibitory activity. These characteristics contribute to consistent blood pressure control throughout the day, potentially allowing for once-daily dosing. Beyond hypertension, Trandolapril has also demonstrated benefits in improving outcomes for patients recovering from a myocardial infarction. For pharmaceutical companies developing treatments for these conditions, sourcing high-purity Trandolapril is essential. When you look to buy Trandolapril, ensure you are getting a product with a purity of ≥99%, typically supplied as a white powder, with the correct CAS number 87679-37-6, molecular formula C24H34N2O5, and molecular weight of 430.54.

Sourcing Trandolapril: Partnering with a Trusted Supplier

Securing a reliable supply of Trandolapril is critical for pharmaceutical development and manufacturing. Identifying a dependable supplier, especially a manufacturer in China, offers a balance of quality and cost-effectiveness. A good partner will provide:

  • Quality Assurance: Verified high purity (≥99%) and comprehensive analytical documentation.
  • Competitive Pricing: Transparent Trandolapril price structures, especially for bulk orders.
  • Reliable Logistics: Efficient global shipping options (Ocean, Land, Air) and consistent delivery schedules.
  • Technical Support: Access to expert advice and necessary documentation.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to being that trusted partner, offering high-quality Trandolapril to meet the stringent demands of the pharmaceutical industry. We empower our clients to effectively manage hypertension and improve cardiovascular health outcomes by ensuring the availability of this vital compound.