Chloroacetonitrile (CAS 107-14-2) is a valuable chemical intermediate widely used in pharmaceutical, agrochemical, and fine chemical manufacturing. However, its inherent toxicity and reactivity necessitate strict adherence to safety protocols for handling and storage. This guide provides essential safety information for industrial users, emphasizing risk mitigation and compliance with regulatory standards.

Understanding the hazards associated with Chloroacetonitrile is the first step towards safe usage. As a toxic chemical, exposure through inhalation, ingestion, or skin contact can lead to severe health consequences. It is crucial for all personnel involved in its handling to be thoroughly trained on its properties and the associated risks. Access to up-to-date Safety Data Sheets (SDS) is mandatory, providing comprehensive details on hazards, first-aid measures, and emergency procedures.

Personal Protective Equipment (PPE): When working with Chloroacetonitrile, appropriate PPE is non-negotiable. This includes chemical-resistant gloves (e.g., nitrile or neoprene), chemical splash goggles, face shields, and protective clothing, such as lab coats or chemical suits. In areas where vapor concentration may be high or ventilation is inadequate, respiratory protection, such as a respirator with an organic vapor cartridge, must be used. Ensure PPE is regularly inspected and maintained in good condition.

Handling Procedures: Always handle Chloroacetonitrile in a well-ventilated area, preferably within a chemical fume hood, to minimize inhalation exposure. Avoid direct contact with skin, eyes, and clothing. Use appropriate dispensing equipment to prevent spills. If a spill occurs, immediately evacuate the area, ensure adequate ventilation, and follow the spill cleanup procedures outlined in the SDS. Trained personnel should handle cleanup using appropriate absorbent materials and PPE.

Storage Recommendations: Chloroacetonitrile should be stored in tightly sealed containers in a cool, dry, and well-ventilated area, away from direct sunlight and heat sources. It must be segregated from incompatible materials, including strong oxidizing agents, acids, bases, and moisture, as contact can lead to hazardous reactions or decomposition. Storage areas should be clearly marked with hazard warnings. Ensure containers are properly labeled and regularly inspected for any signs of damage or leakage.

Emergency Preparedness: Facilities handling Chloroacetonitrile must have robust emergency plans in place. This includes readily accessible eyewash stations and safety showers, as well as appropriate fire extinguishers (e.g., dry chemical, CO₂, or foam) suitable for chemical fires. Personnel should be trained in emergency response procedures, including spill containment and evacuation protocols. For businesses looking to purchase Chloroacetonitrile, selecting a manufacturer with a strong commitment to safety and providing comprehensive safety guidance is a critical factor in ensuring responsible industrial use.