The safe handling and storage of chemical intermediates are paramount in any industrial or research setting. 3-Fluoro-4-bromobenzyl bromide (CAS 127425-73-4) is a chemical that, while highly useful, requires careful attention to safety protocols. This guide outlines the essential safety information and handling procedures for this compound, crucial for R&D scientists, laboratory technicians, and procurement managers to ensure a safe working environment and compliance with regulations.

Hazard Identification and Classification

According to GHS classification, 3-Fluoro-4-bromobenzyl bromide is recognized for its hazardous properties. Key hazard statements include:

  • H314: Causes severe skin burns and eye damage. This indicates that direct contact can lead to significant corrosive effects on skin and eyes.
  • H318: Causes serious eye damage. Even brief eye contact can result in severe irritation or irreversible damage.

The compound is classified under Hazard Class 8 (Corrosive substances), and often falls under UN3261 for transportation, typically as a corrosive solid, acidic, organic, N.O.S. It is essential to consult the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) provided by the supplier for detailed information on specific hazards and emergency procedures.

Safe Handling Procedures

When working with 3-Fluoro-4-bromobenzyl bromide, adherence to the following handling procedures is critical:

  • Personal Protective Equipment (PPE): Always wear appropriate PPE, including chemical-resistant gloves (e.g., nitrile, neoprene), safety goggles or a face shield to protect the eyes, and protective clothing (lab coat, apron) to prevent skin contact.
  • Ventilation: Work only in a well-ventilated area, preferably within a chemical fume hood, to avoid inhalation of vapors or dust.
  • Minimizing Exposure: Avoid breathing dust, fume, gas, mist, vapors, or spray. Take all necessary precautions to avoid contact with skin and eyes. Ensure adequate eyewash stations and safety showers are readily accessible.
  • Hygiene: Wash hands thoroughly after handling and before eating, drinking, or smoking. Contaminated clothing should be removed immediately and washed before reuse.

Storage Recommendations

Proper storage is vital to maintain the compound's integrity and prevent accidents:

  • Container: Store in tightly closed vessels.
  • Conditions: Keep in a cool, dry, well-ventilated place. Recommended storage temperatures are typically between 2-8°C, under an inert gas (nitrogen or argon) to prevent degradation or reaction with moisture.
  • Incompatibility: Keep away from incompatible materials such as strong oxidizing agents.

Emergency Procedures

  • Skin Contact: Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing. Seek medical attention if irritation persists.
  • Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, ensuring eyelids are held open. Remove contact lenses if present and easy to do. Seek immediate medical attention.
  • Inhalation: Remove to fresh air. If breathing is difficult, administer oxygen. Seek medical attention.
  • Ingestion: Rinse mouth with water. Do NOT induce vomiting. Seek immediate medical attention.

As a responsible supplier of 3-Fluoro-4-bromobenzyl bromide (CAS 127425-73-4), we provide comprehensive safety data sheets to all our customers. Understanding and implementing these safety guidelines is crucial for anyone working with this chemical. We encourage all users to prioritize safety and seek professional advice when handling hazardous materials.