The efficacy of chemical intermediates lies in their precise structure and reactivity, enabling the synthesis of complex molecules. 2-Fluorobenzophenone (CAS 342-24-5) exemplifies this, serving as a crucial component in various advanced chemical processes. Understanding its properties and synthesis pathways is fundamental for chemists and procurement specialists.

2-Fluorobenzophenone is an aromatic ketone characterized by a benzophenone structure featuring a fluorine atom at the ortho position of one phenyl ring. This fluorine substitution significantly influences the molecule's electronic properties and reactivity. Its molecular formula is C13H9FO, with a molecular weight of approximately 200.21 g/mol. Typically supplied as a white powder, it possesses a melting point that makes it a stable solid at room temperature, simplifying handling and storage. The product's density is around 1.186 g/cm³, and its boiling point is approximately 149-150°C at 16 mmHg, indicating its thermal stability under controlled conditions.

The synthesis of 2-Fluorobenzophenone often involves Friedel-Crafts acylation reactions. One common method involves the reaction of fluorobenzene with benzoyl chloride in the presence of a Lewis acid catalyst, such as aluminum chloride. Alternatively, it can be synthesized from 2-fluorobenzoyl chloride and benzene. These processes require careful control of reaction conditions, including temperature and catalyst concentration, to ensure high yields and purity. When seeking to buy 2-Fluorobenzophenone, it is vital to inquire about the manufacturing process from the manufacturer to ensure it meets desired quality standards.

The chemical properties of 2-Fluorobenzophenone make it a versatile intermediate for further synthetic modifications. The carbonyl group can undergo reduction, Grignard reactions, and Wittig reactions, while the aromatic rings can be subjected to electrophilic aromatic substitution. The presence of the fluorine atom can also facilitate nucleophilic aromatic substitution under specific conditions. These reactivities are leveraged extensively in the synthesis of pharmaceuticals and agrochemicals, where precise molecular architecture is paramount.

For those involved in sourcing, understanding the technical specifications and safety data of CAS 342-24-5 is crucial. A reputable supplier will provide detailed information, including purity levels (often >98%), as well as comprehensive SDS and TDS. The term 2-fluorophenyl phenyl methanone is a synonym that highlights its structural composition. Ensuring that the sourced material aligns with industry standards like USP, BP, or FCC is essential for compliance.

The global supply of 2-Fluorobenzophenone is significantly influenced by manufacturing capabilities, particularly in regions like China. By partnering with a reliable manufacturer, companies can secure a consistent supply of this important intermediate at competitive price points. This strategic sourcing ensures that research and production activities can proceed without disruption, supporting ongoing innovation in chemistry.

In conclusion, 2-Fluorobenzophenone is a compound of significant chemical interest due to its unique properties and synthetic versatility. Its reliable production and availability are key to advancing fields such as pharmaceuticals and agrochemicals. We encourage potential buyers to consult with us for high-quality 2-Fluorobenzophenone and to inquire about pricing and supply chain solutions from our trusted Chinese manufacturing base.